MAFG

MAFG
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1K1V, 3A5T
Dynodwyr
Cyfenwau	MAFG, hMAF, MAF bZIP transcription factor G
Dynodwyr allanol	OMIM: 602020 HomoloGene: 81816 GeneCards: MAFG
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • DNA binding; • GO:0001948, GO:0016582 protein binding; • protein heterodimerization activity; • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific; • sequence-specific DNA binding;
Cydrannau o'r gell	• nucleoplasm; • cnewyllyn cell;
Prosesau biolegol	• regulation of epidermal cell differentiation; • GO:1901313 positive regulation of gene expression; • adult behavior; • blood coagulation; • in utero embryonic development; • regulation of cell population proliferation; • regulation of cellular pH; • GO:0009373 regulation of transcription, DNA-templated; • transcription, DNA-templated; • transcription by RNA polymerase II; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologau
	4097
	n/a
	ENSG00000197063
	n/a
	O15525
	n/a
	NM_002359; NM_032711
	n/a
	NP_002350; NP_116100
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MAFG yw MAFG a elwir hefyd yn MAF bZIP transcription factor G (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q25.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MAFG.

hMAF

Llyfryddiaeth

"Picosecond-hetero-FRET microscopy to probe protein-protein interactions in live cells. ". Biophys J. 2002. PMID 12496124.
"Molecular characterization and localization of the human MAFG gene. ". Genomics. 1997. PMID 9286713.
"hMAF, a small human transcription factor that heterodimerizes specifically with Nrf1 and Nrf2. ". J Biol Chem. 1997. PMID 9195958.
"The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotype. ". Mol Cell. 2014. PMID 25219500.
"Small MAF genes variants and chronic myeloid leukemia.". Eur J Haematol. 2014. PMID 24118457.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] MAFG - Cronfa NCBI

[1]

[2]