MMP3

MMP3
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1B3D, 1B8Y, 1BIW, 1BM6, 1BQO, 1C3I, 1C8T, 1CAQ, 1CIZ, 1CQR, 1D5J, 1D7X, 1D8F, 1D8M, 1G05, 1G49, 1G4K, 1HFS, 1HY7, 1OO9, 1QIA, 1QIC, 1SLM, 1SLN, 1UEA, 1UMS, 1UMT, 1USN, 2D1O, 2JNP, 2JT5, 2JT6, 2SRT, 2USN, 3OHL, 3OHO, 3USN, 4DPE, 4G9L, 4JA1
Dynodwyr
Cyfenwau	MMP3, CHDS6, MMP-3, SL-1, STMY, STMY1, STR1, matrix metallopeptidase 3
Dynodwyr allanol	OMIM: 185250 HomoloGene: 20545 GeneCards: MMP3
EC number	3.4.24.17
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• zinc ion binding; • GO:0070122 peptidase activity; • endopeptidase activity; • metalloendopeptidase activity; • GO:0001948, GO:0016582 protein binding; • hydrolase activity; • metal ion binding; • serine-type endopeptidase activity; • metallopeptidase activity;
Cydrannau o'r gell	• GO:0005578 extracellular matrix; • extracellular region; • extracellular space;
Prosesau biolegol	• collagen catabolic process; • cellular response to nitric oxide; • negative regulation of hydrogen peroxide metabolic process; • extracellular matrix disassembly; • proteolysis; • positive regulation of protein oligomerization; • positive regulation of oxidative stress-induced cell death; • cytokine-mediated signaling pathway; • response to hypoxia; • regulation of cell migration; • regulation of neuroinflammatory response; • extracellular matrix organization; • response to amyloid-beta;
	Sources:Amigo / QuickGO
Orthologau
	4314
	n/a
	ENSG00000149968
	n/a
	P08254
	n/a
	NM_002422
	n/a
	NP_002413
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MMP3 yw MMP3 a elwir hefyd yn Matrix metallopeptidase 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q22.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MMP3.

SL-1
STMY
STR1
CHDS6
MMP-3
STMY1

Llyfryddiaeth

"Elevated expression of matrix metalloproteinase-3 in human osteosarcoma and its association with tumor metastasis. ". J BUON. 2016. PMID 27837634.
"The Effect of Matrix Metalloproteinase-3 on the Prognosis and Biological Behaviour of Meningiomas. ". Turk Neurosurg. 2016. PMID 27438616.
"Evaluation of serum matrix metalloproteinase-3 as a biomarker for diagnosis of epilepsy. ". J Neurol Sci. 2016. PMID 27423606.
"The MMP3 gene in musculoskeletal soft tissue injury risk profiling: A study in two independent sample groups. ". J Sports Sci. 2017. PMID 27211292.
"MMP3 -1171 5A/6A Promoter Genotype Influences Serum MMP3 Levels and Is Associated with Deep Venous Thrombosis.". Ann Vasc Surg. 2016. PMID 27177702.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] MMP3 - Cronfa NCBI

[1]

[2]