MPP1

MPP1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2EJY, 2EV8, 3NEY
Dynodwyr
Cyfenwau	MPP1, AAG12, DXS552E, EMP55, MRG1, PEMP, membrane palmitoylated protein 1, MAGUK p55 scaffold protein 1
Dynodwyr allanol	OMIM: 305360 HomoloGene: 1826 GeneCards: MPP1
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• guanylate kinase activity; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• cortical cytoskeleton; • cell projection; • integral component of plasma membrane; • intracellular anatomical structure; • bilen; • stereocilium; • cytosol; • Cellbilen; • nuclear speck;
Prosesau biolegol	• regulation of neutrophil chemotaxis; • GO:0072468 signal transduction; • GDP metabolic process; • GMP metabolic process;
	Sources:Amigo / QuickGO
Orthologau
	4354
	n/a
	ENSG00000130830
	n/a
	Q00013
	n/a
	NM_001166460; NM_001166461; NM_001166462; NM_002436
	n/a
	NP_001159932; NP_001159933; NP_001159934; NP_002427
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MPP1 yw MPP1 a elwir hefyd yn Membrane palmitoylated protein 1 a 55 kDa erythrocyte membrane protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xq28.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MPP1.

MRG1
PEMP
AAG12
EMP55
DXS552E

Llyfryddiaeth

"MPP1 directly interacts with flotillins in erythrocyte membrane - Possible mechanism of raft domain formation. ". Biochim Biophys Acta. 2017. PMID 28865798.
"MPP1 interacts with DOPC/SM/Cholesterol in an artificial membrane system using Langmuir-Blodgett monolayer. ". Gen Physiol Biophys. 2017. PMID 28653654.
"Membrane rafts in the erythrocyte membrane: a novel role of MPP1p55. ". Adv Exp Med Biol. 2015. PMID 25408337.
"The role of MPP1/p55 and its palmitoylation in resting state raft organization in HEL cells. ". Biochim Biophys Acta. 2013. PMID 23507198.
"Palmitoylation of MPP1 (membrane-palmitoylated protein 1)/p55 is crucial for lateral membrane organization in erythroid cells.". J Biol Chem. 2012. PMID 22496366.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] MPP1 - Cronfa NCBI

[1]

[2]