NFYC

NFYC
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1N1J, 4AWL, 4CSR
Dynodwyr
Cyfenwau	NFYC, CBF-C, CBFC, H1TF2A, HAP5, HSM, NF-YC, nuclear transcription factor Y subunit gamma
Dynodwyr allanol	OMIM: 605344 HomoloGene: 7440 GeneCards: NFYC
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • DNA binding; • GO:0001105 transcription coactivator activity; • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific; • GO:0001948, GO:0016582 protein binding; • protein heterodimerization activity; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific; • transcription factor binding; • sequence-specific DNA binding;
Cydrannau o'r gell	• CCAAT-binding factor complex; • protein-DNA complex; • cnewyllyn cell; • nucleoplasm; • RNA polymerase II transcription regulator complex;
Prosesau biolegol	• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II; • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated; • GO:0009373 regulation of transcription, DNA-templated; • transcription by RNA polymerase II; • protein folding; • transcription, DNA-templated; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • regulation of cholesterol biosynthetic process; • GO:0045996 negative regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologau
	4802
	n/a
	ENSG00000066136
	n/a
	Q13952
	n/a
NM_001142587; NM_001142588; NM_001142589; NM_001142590; NM_001308114;
	NM_001308115; NM_014223
	n/a
NP_001136059; NP_001136060; NP_001136061; NP_001136062; NP_001295043;
	NP_001295044; NP_055038
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NFYC yw NFYC a elwir hefyd yn Nuclear transcription factor Y subunit gamma (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p34.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NFYC.

HSM
CBFC
HAP5
CBF-C
NF-YC
H1TF2A

Llyfryddiaeth

"NF-YC in glioma cell proliferation and tumor growth and its role as an independent predictor of patient survival. ". Neurosci Lett. 2016. PMID 27495011.
"NF-YC complexity is generated by dual promoters and alternative splicing. ". J Biol Chem. 2009. PMID 19690168.
"C/EBPbeta contributes to hepatocyte growth factor-induced replication of rodent hepatocytes. ". J Hepatol. 2005. PMID 15922473.
"Isolation and sequence analysis of the cDNA encoding subunit C of human CCAAT-binding transcription factor. ". Gene. 1997. PMID 9332362.
"Cloning and expression of human NF-YC.". Gene. 1997. PMID 9249075.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] NFYC - Cronfa NCBI

[1]

[2]