NPY1R

NPY1R
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2F1U, 2IIL
Dynodwyr
Cyfenwau	NPY1R, NPY1-R, NPYR, Neuropeptide Y receptor Y1
Dynodwyr allanol	OMIM: 162641 HomoloGene: 700 GeneCards: NPY1R
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• neuropeptide Y receptor activity; • G protein-coupled receptor activity; • signal transducer activity; • GO:0001948, GO:0016582 protein binding; • peptide YY receptor activity; • pancreatic polypeptide receptor activity;
Cydrannau o'r gell	• integral component of membrane; • bilen; • Cellbilen; • integral component of plasma membrane;
Prosesau biolegol	• adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; • locomotory behavior; • regulation of multicellular organism growth; • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; • outflow tract morphogenesis; • blood circulation; • regulation of blood pressure; • feeding behavior; • glucose metabolic process; • sensory perception of pain; • neuropeptide signaling pathway; • GO:0072468 signal transduction; • chemical synaptic transmission; • G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologau
	4886
	n/a
	ENSG00000164128
	n/a
	P25929
	n/a
	NM_000909
	n/a
	NP_000900
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NPY1R yw NPY1R a elwir hefyd yn Neuropeptide Y receptor type 1 a Neuropeptide Y receptor Y1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q32.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NPY1R.

NPYR
NPY1-R

Llyfryddiaeth

"Neuropeptide Y1 receptor inhibits cell growth through inactivating mitogen-activated protein kinase signal pathway in human hepatocellular carcinoma. ". Med Oncol. 2016. PMID 27262566.
"Toward Labeled Argininamide-Type NPY Y1 Receptor Antagonists: Identification of a Favorable Propionylation Site in BIBO3304. ". Arch Pharm (Weinheim). 2015. PMID 25884646.
"Neuropeptide Y receptor mediates activation of ERK1/2 via transactivation of the IGF receptor. ". Cell Signal. 2015. PMID 25817573.
"Knockdown of a G protein-coupled receptor through efficient peptide-mediated siRNA delivery. ". J Control Release. 2012. PMID 22626516.
"Neuropeptide Y Y1 receptor hippocampal overexpression via viral vectors is associated with modest anxiolytic-like and proconvulsant effects in mice.". J Neurosci Res. 2012. PMID 21971867.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] NPY1R - Cronfa NCBI

[1]

[2]