NRCAM

NRCAM
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1UEN, 1UEY
Dynodwyr
Cyfenwau	NRCAM, neuronal cell adhesion molecule
Dynodwyr allanol	OMIM: 601581 HomoloGene: 21041 GeneCards: NRCAM
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • protein binding involved in heterotypic cell-cell adhesion; • ankyrin binding;
Cydrannau o'r gell	• integral component of membrane; • cell projection; • bilen; • Cellbilen; • synapse; • integral component of plasma membrane; • extracellular region; • axon; • neuron projection; • axon initial segment; • external side of plasma membrane; • glutamatergic synapse; • integral component of postsynaptic membrane; • integral component of postsynaptic density membrane;
Prosesau biolegol	• GO:0034613 protein localization; • clustering of voltage-gated sodium channels; • regulation of neuron projection development; • regulation of axon extension; • axonogenesis; • heterotypic cell-cell adhesion; • neuron migration; • central nervous system development; • cell adhesion; • neuronal action potential propagation; • angiogenesis; • positive regulation of neuron differentiation; • synapse assembly; • axonal fasciculation; • retinal ganglion cell axon guidance; • axon guidance; • cell-cell adhesion; • regulation of postsynapse organization;
	Sources:Amigo / QuickGO
Orthologau
	4897
	n/a
	ENSG00000091129
	n/a
	Q92823
	n/a
NM_001037132; NM_001037133; NM_001193582; NM_001193583; NM_001193584;
	NM_005010
	n/a
NP_001032209; NP_001180511; NP_001180512; NP_001180513; NP_005001;
	NP_001358048; NP_001358051; NP_001358052; NP_001358053; NP_001358054; NP_001358055; NP_001358056; NP_001358057; NP_001358058; NP_001358059; NP_001358060; NP_001358061; NP_001358062; NP_001358063; NP_001358064; NP_001358065; NP_001358066; NP_001358067; NP_001358068; NP_001358069; NP_001358070; NP_001358071; NP_001358072; NP_001358073; NP_001358074; NP_001358075; NP_001358076; NP_001358077; NP_001358078; NP_001358079; NP_001358080; NP_001358081; NP_001358082; NP_001358083; NP_001358084; NP_001358085; NP_001358086; NP_001358087; NP_001358088; NP_001358089; NP_001358090; NP_001358091; NP_001358092; NP_001358093; NP_001358094; NP_001358095; NP_001358096; NP_001358097; NP_001358098; NP_001358099; NP_001358100; NP_001358101; NP_001358102; NP_001358103; NP_001358104; NP_001358105; NP_001358106; NP_001358107; NP_001358108; NP_001358109; NP_001358110; NP_001358111
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NRCAM yw NRCAM a elwir hefyd yn Neuronal cell adhesion molecule (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7q31.1.^[2]

Llyfryddiaeth

"Implications of NOVA1 suppression within the microenvironment of gastric cancer: association with immune cell dysregulation.". Gastric Cancer. 2017. PMID 27318497.
"MiR-181b-5p downregulates NOVA1 to suppress proliferation, migration and invasion and promote apoptosis in astrocytoma.". PLoS One. 2014. PMID 25299073.
"High expression of neuro-oncological ventral antigen 1 correlates with poor prognosis in hepatocellular carcinoma. ". PLoS One. 2014. PMID 24608171.
"Paraneoplastic antibody during follow-up of a patient with anti-Ri-associated paraneoplastic neurological syndrome.". Acta Neurol Scand. 2009. PMID 18822086.
"The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo.". Mol Cell Biol,. 1997. PMID 9154818.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] NRCAM - Cronfa NCBI

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[2]