PEX19

PEX19
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2W85, 2WL8, 3AJB, 3MK4
Dynodwyr
Cyfenwau	PEX19, D1S2223E, HK33, PBD12A, PMP1, PMPI, PXF, PXMP1, peroxisomal biogenesis factor 19
Dynodwyr allanol	OMIM: 600279 HomoloGene: 134253 GeneCards: PEX19
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• peroxisome membrane class-1 targeting sequence binding; • protein N-terminus binding; • ATPase binding; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• cytoplasm; • integral component of membrane; • cytosol; • bilen; • peroxisomal membrane; • peroxisome; • nucleoplasm; • brush border membrane; • cnewyllyn cell; • GO:0009327 protein-containing complex;
Prosesau biolegol	• protein targeting to peroxisome; • peroxisome organization; • protein stabilization; • peroxisome membrane biogenesis; • peroxisome fission; • protein import into peroxisome membrane; • transmembrane transport; • establishment of protein localization to peroxisome; • negative regulation of lipid binding; • chaperone-mediated protein folding;
	Sources:Amigo / QuickGO
Orthologau
	5824
	n/a
	ENSG00000162735
	n/a
	P40855
	n/a
	NM_001131039; NM_001193644; NM_002857
	n/a
	NP_001180573; NP_002848
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PEX19 yw PEX19 a elwir hefyd yn Peroxisomal biogenesis factor 19 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q23.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PEX19.

PXF
HK33
PMP1
PMPI
PXMP1
PBD12A
D1S2223E

Llyfryddiaeth

"The import competence of a peroxisomal membrane protein is determined by Pex19p before the docking step. ". J Biol Chem. 2006. PMID 16980692.
"Functional domains and dynamic assembly of the peroxin Pex14p, the entry site of matrix proteins. ". J Biol Chem. 2006. PMID 16459329.
"A mutation in PEX19 causes a severe clinical phenotype in a patient with peroxisomal biogenesis disorder. ". Am J Med Genet A. 2010. PMID 20683989.
"Elevated delta-6 desaturase (FADS2) expression in the postmortem prefrontal cortex of schizophrenic patients: relationship with fatty acid composition. ". Schizophr Res. 2009. PMID 19195843.
"Import of peroxisomal membrane proteins: the interplay of Pex3p- and Pex19p-mediated interactions.". Biochim Biophys Acta. 2006. PMID 17069900.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] PEX19 - Cronfa NCBI

[1]

[2]