PPP5C

PPP5C
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1A17, 1S95, 1WAO, 2BUG, 3H60, 3H61, 3H62, 3H63, 3H64, 3H66, 3H67, 3H68, 3H69, 4ZX2, 4ZVZ
Dynodwyr
Cyfenwau	PPP5C, PP5, PPP5, PPT, protein phosphatase 5 catalytic subunit
Dynodwyr allanol	OMIM: 600658 HomoloGene: 4550 GeneCards: PPP5C
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• phosphoprotein phosphatase activity; • heat shock protein binding; • microtubule binding; • ADP binding; • protein serine/threonine phosphatase activity; • signal transducer activity; • metal ion binding; • GO:0001948, GO:0016582 protein binding; • RNA binding; • identical protein binding; • G-protein alpha-subunit binding; • hydrolase activity; • ATP binding; • lipid binding; • Hsp90 protein binding;
Cydrannau o'r gell	• perikaryon; • bilen; • intracellular membrane-bounded organelle; • Cellbilen; • soma; • proximal dendrite; • neuron projection; • cnewyllyn cell; • cyrion cell; • nucleoplasm; • cytoplasm; • cytosol;
Prosesau biolegol	• GO:0033128 negative regulation of protein phosphorylation; • positive regulation of glucocorticoid receptor signaling pathway; • protein heterooligomerization; • GO:0016576 protein dephosphorylation; • negative regulation of cell death; • cellular response to cadmium ion; • transcription, DNA-templated; • MAPK cascade; • cellular response to DNA damage stimulus; • response to morphine; • response to lead ion; • protein complex oligomerization; • positive regulation of I-kappaB kinase/NF-kappaB signaling; • cellular response to hydrogen peroxide; • negative regulation of neuron death; • GO:0100026 DNA repair; • GO:0007067 Mitosis;
	Sources:Amigo / QuickGO
Orthologau
	5536
	n/a
	ENSG00000011485
	n/a
	P53041
	n/a
	NM_006247; NM_001204284
	n/a
	NP_001191213; NP_006238
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PPP5C yw PPP5C a elwir hefyd yn Protein phosphatase 5 catalytic subunit (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19q13.32.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PPP5C.

PP5
PPT
PPP5

Llyfryddiaeth

"Serine/Threonine Protein Phosphatase-5 Accelerates Cell Growth and Migration in Human Glioma. ". Cell Mol Neurobiol. 2015. PMID 25796168.
"Knockdown of PPP5C inhibits growth of hepatocellular carcinoma cells in vitro. ". Appl Biochem Biotechnol. 2015. PMID 25326185.
"Cytokine-Induced Glucocorticoid Resistance from Eosinophil Activation: Protein Phosphatase 5 Modulation of Glucocorticoid Receptor Phosphorylation and Signaling. ". J Immunol. 2016. PMID 27742828.
"Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma. ". Allergy. 2017. PMID 27501780.
"Measles Virus Infection Inactivates Cellular Protein Phosphatase 5 with Consequent Suppression of Sp1 and c-Myc Activities.". J Virol. 2015. PMID 26157124.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] PPP5C - Cronfa NCBI

[1]

[2]