PRC1

PRC1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3NRX, 3NRY, 4L3I, 4L6Y
Dynodwyr
Cyfenwau	PRC1, ASE1, protein regulator of cytokinesis 1
Dynodwyr allanol	OMIM: 603484 HomoloGene: 37868 GeneCards: PRC1
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• protein kinase binding; • identical protein binding; • kinesin binding; • microtubule binding; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• spindle; • cytosol; • spindle pole; • microtubule; • spindle microtubule; • contractile ring; • Cytosgerbwd; • cnewyllyn cell; • midbody; • cytoplasm;
Prosesau biolegol	• microtubule bundle formation; • cell cycle; • Cellraniad; • microtubule cytoskeleton organization; • mitotic spindle elongation; • positive regulation of cell population proliferation; • cytokinesis; • regulation of cytokinesis;
	Sources:Amigo / QuickGO
Orthologau
	9055
	n/a
	ENSG00000198901
	n/a
	O43663
	n/a
	NM_001267580; NM_003981; NM_199413; NM_199414
	n/a
	NP_001254509; NP_003972; NP_955445
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PRC1 yw PRC1 a elwir hefyd yn Protein regulator of cytokinesis 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 15, band 15q26.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PRC1.

ASE1

Llyfryddiaeth

"The BEG (PP2A-B55/ENSA/Greatwall) pathway ensures cytokinesis follows chromosome separation. ". Mol Cell. 2013. PMID 24120663.
"Nonredundant and locus-specific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells. ". Blood. 2013. PMID 23349393.
"Genetic and functional analyses do not explain the association of high PRC1 expression with poor survival of breast carcinoma patients. ". Biomed Pharmacother. 2016. PMID 27505863.
"The microtubule-associated protein PRC1 promotes early recurrence of hepatocellular carcinoma in association with the Wnt/β-catenin signalling pathway. ". Gut. 2016. PMID 26941395.
"Protein regulator of cytokinesis 1 overexpression predicts biochemical recurrence in men with prostate cancer.". Biomed Pharmacother. 2016. PMID 26898432.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] PRC1 - Cronfa NCBI

[1]

[2]