PRKACB

PRKACB
Dynodwyr
Cyfenwau	PRKACB, PKA C-beta, PKACB, protein kinase cAMP-activated catalytic subunit beta, CAFD2
Dynodwyr allanol	OMIM: 176892 HomoloGene: 121718 GeneCards: PRKACB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • protein kinase activity • cAMP-dependent protein kinase activity • GO:0001948, GO:0016582 protein binding • ATP binding • ubiquitin protein ligase binding • magnesium ion binding • kinase activity • protein serine/threonine kinase activity • protein kinase A regulatory subunit binding Cydrannau o'r gell • cytoplasm • centrosome • bilen • Cellbilen • nucleoplasm • ciliary base • perinuclear region of cytoplasm • cAMP-dependent protein kinase complex • extracellular exosome • cnewyllyn cell • cytosol • intercellular bridge Prosesau biolegol • negative regulation of meiotic cell cycle • activation of protein kinase A activity • phosphorylation • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • cellular response to glucagon stimulus • negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning • blood coagulation • stimulatory C-type lectin receptor signaling pathway • regulation of protein processing • protein phosphorylation • neural tube closure • response to clozapine • renal water homeostasis • GO:0072468 signal transduction • high-density lipoprotein particle assembly • G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5567	n/a
Ensembl	ENSG00000142875	n/a
UniProt	P22694	n/a
RefSeq (mRNA)	NM_001242857 NM_001242858 NM_001242859 NM_001242860 NM_001242861 NM_001242862 NM_001300915 NM_001300916 NM_001300917 NM_002731 NM_182948 NM_207578 NM_001375560 NM_001375561 NM_001375562 NM_001375563 NM_001375564 NM_001375565 NM_001375569 NM_001375571 NM_001375572 NM_001375573 NM_001375574 NM_001375575 NM_001375576 NM_001375577 NM_001375578 NM_001375579 NM_001375580 NM_001375581	n/a
RefSeq (protein)	NP_001229786 NP_001229787 NP_001229788 NP_001229789 NP_001229790 NP_001229791 NP_001287844 NP_001287845 NP_001287846 NP_002722 NP_891993 NP_997461 NP_001362489 NP_001362490 NP_001362491 NP_001362492 NP_001362493 NP_001362494 NP_001362498 NP_001362500 NP_001362501 NP_001362502 NP_001362503 NP_001362504 NP_001362505 NP_001362506 NP_001362507 NP_001362508 NP_001362509 NP_001362510 NP_002722.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PRKACB yw PRKACB a elwir hefyd yn Protein kinase, cAMP-dependent, catalytic, beta, isoform CRA_a a Protein kinase cAMP-activated catalytic subunit beta (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p31.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PRKACB.

• PKACB
• PKA*C-beta

Llyfryddiaeth

• "The cAMP-dependent protein kinase A and protein kinase C-beta pathways synergistically interact to activate HIV-1 transcription in latently infected cells of monocyte/macrophage lineage. ". Virology. 1998. PMID 9636365.
• "The major catalytic subunit isoforms of cAMP-dependent protein kinase have distinct biochemical properties in vitro and in vivo. ". J Biol Chem. 1996. PMID 8662989.
• "Association between PKA gene polymorphism and NTDs in high risk Chinese population in Shanxi. ". Int J Clin Exp Pathol. 2013. PMID 24294386.
• "Androgen dependent regulation of protein kinase A subunits in prostate cancer cells. ". Cell Signal. 2007. PMID 16949795.
• "Identification of novel splice variants of the human catalytic subunit Cbeta of cAMP-dependent protein kinase.". Eur J Biochem. 2001. PMID 11589697.

Cyfeiriadau

1. "Human PubMed Reference:".
2. PRKACB - Cronfa NCBI