RAB23

RAB23
Dynodwyr
Cyfenwau	RAB23, HSPC137, member RAS oncogene family
Dynodwyr allanol	OMIM: 606144 HomoloGene: 7503 GeneCards: RAB23
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • GTP binding; • GO:0001948, GO:0016582 protein binding; • GO:0006184 GTPase activity;
Cydrannau o'r gell	• cytoplasm; • endosome; • phagocytic vesicle membrane; • bilen; • Cellbilen; • autophagosome; • phagocytic vesicle; • endosome membrane; • GO:0016023 cytoplasmic vesicle; • centrosome; • cytosol; • cell junction;
Prosesau biolegol	• craniofacial suture morphogenesis; • autophagosome assembly; • multicellular organism development; • cellular defense response; • protein transport; • cilium assembly; • GTP metabolic process; • negative regulation of protein import into nucleus; • intracellular protein transport; • Rab protein signal transduction; • GO:0072468 signal transduction;
	Sources:Amigo / QuickGO
Orthologau
	51715
	n/a
	ENSG00000112210
	n/a
	Q9ULC3
	n/a
	NM_001278666; NM_001278667; NM_001278668; NM_016277; NM_183227
	n/a
	NP_001265595; NP_001265596; NP_001265597; NP_057361; NP_899050
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB23 yw RAB23 a elwir hefyd yn RAB23, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p12.1-p11.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAB23.

HSPC137

Llyfryddiaeth

"[Role of Rab23 in invasion and migration of human breast cancer Bcap-37 cells]. ". Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2013. PMID 23948406.
"A Novel Aberrant Splice Site Mutation in RAB23 Leads to an Eight Nucleotide Deletion in the mRNA and Is Responsible for Carpenter Syndrome in a Consanguineous Emirati Family. ". Mol Syndromol. 2013. PMID 23599695.
"Downregulation of Rab23 in Prostate Cancer Inhibits Tumor Growth In Vitro and In Vivo. ". Oncol Res. 2017. PMID 28277196.
"Rab23 is overexpressed in human bladder cancer and promotes cancer cell proliferation and invasion. ". Tumour Biol. 2016. PMID 26715272.
"Inactivation of Rab23 inhibits the invasion and motility of pancreatic duct adenocarcinoma.". Genet Mol Res. 2015. PMID 25867419.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RAB23 - Cronfa NCBI

[1]

[2]