RAB33B

RAB33B
Dynodwyr
Cyfenwau	RAB33B, SMC2, member RAS oncogene family
Dynodwyr allanol	OMIM: 605950 HomoloGene: 9642 GeneCards: RAB33B
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • nucleotide binding; • GTP binding; • GO:0006184 GTPase activity;
Cydrannau o'r gell	• bilen; • Golgi lumen; • Golgi apparatus; • Golgi membrane; • presynapse; • endoplasmic reticulum membrane;
Prosesau biolegol	• negative regulation of constitutive secretory pathway; • regulation of Golgi organization; • intra-Golgi vesicle-mediated transport; • regulation of epithelial cell proliferation; • regulation of retrograde vesicle-mediated transport, Golgi to ER; • protein transport; • skeletal system morphogenesis; • autophagy; • regulation of cell growth; • autophagosome assembly; • regulation of autophagosome assembly; • protein localization to Golgi apparatus; • intracellular protein transport; • endoplasmic reticulum to Golgi vesicle-mediated transport; • Rab protein signal transduction;
	Sources:Amigo / QuickGO
Orthologau
	83452
	n/a
	ENSG00000172007
	n/a
	Q9H082
	n/a
	NM_031296
	n/a
	NP_112586
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB33B yw RAB33B a elwir hefyd yn RAB33B, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4q31.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAB33B.

SMC2

Llyfryddiaeth

"Deciphering the role of Atg5 in nucleotide dependent interaction of Rab33B with the dimeric complex, Atg5-Atg16L1. ". Biochem Biophys Res Commun. 2016. PMID 26975471.
"Rab33B and its autophagic Atg5/12/16L1 effector assist in hepatitis B virus naked capsid formation and release. ". Cell Microbiol. 2015. PMID 25439980.
"Additional three patients with Smith-McCort dysplasia due to novel RAB33B mutations. ". Am J Med Genet A. 2017. PMID 28127940.
"Mutation in RAB33B, which encodes a regulator of retrograde Golgi transport, defines a second Dyggve--Melchior--Clausen locus. ". J Med Genet. 2012. PMID 22652534.
"A novel RAB33B mutation in Smith-McCort dysplasia.". Hum Mutat. 2013. PMID 23042644.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RAB33B - Cronfa NCBI

[1]

[2]