RAB3A

RAB3A
Dynodwyr
Cyfenwau	RAB3A, member RAS oncogene family
Dynodwyr allanol	OMIM: 179490 HomoloGene: 20629 GeneCards: RAB3A
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • ATPase binding; • GTP binding; • myosin V binding; • protein C-terminus binding; • GO:0001948, GO:0016582 protein binding; • ATPase activator activity; • GTP-dependent protein binding; • GO:0006184 GTPase activity; • GDP-dissociation inhibitor binding;
Cydrannau o'r gell	• extracellular vesicle; • endosome; • clathrin-sculpted monoamine transport vesicle membrane; • bilen; • synaptic vesicle; • Cellbilen; • clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane; • clathrin-sculpted acetylcholine transport vesicle membrane; • axon; • terminal bouton; • acrosomal vesicle; • intracellular organelle; • clathrin-sculpted glutamate transport vesicle membrane; • cytosol; • secretory granule membrane; • anchored component of synaptic vesicle membrane; • fesigl; • GO:0009327 protein-containing complex; • presynaptic active zone; • secretory granule; • perinuclear region of cytoplasm;
Prosesau biolegol	• respiratory system process; • positive regulation of ATP-dependent activity; • axonogenesis; • lung development; • synaptic vesicle exocytosis; • regulation of short-term neuronal synaptic plasticity; • evoked neurotransmitter secretion; • mitochondrion organization; • response to electrical stimulus; • post-embryonic development; • constitutive secretory pathway; • maintenance of presynaptic active zone structure; • glutamate secretion; • regulation of exocytosis; • regulation of synaptic vesicle fusion to presynaptic active zone membrane; • neuromuscular synaptic transmission; • synaptic vesicle recycling; • sensory perception of touch; • protein transport; • positive regulation of exocytosis; • synaptic vesicle maturation; • GO:0010554 neurotransmitter secretion; • positive regulation of regulated secretory pathway; • exocytosis; • neutrophil degranulation; • post-translational protein modification; • GO:0015915 transport; • intracellular protein transport; • vesicle docking involved in exocytosis; • protein secretion; • Rab protein signal transduction; • protein localization to plasma membrane; • plasma membrane repair; • regulation of synaptic vesicle priming; • synaptic vesicle transport; • acrosomal vesicle exocytosis; • regulation of synaptic vesicle exocytosis; • calcium-ion regulated exocytosis; • synaptic vesicle clustering;
	Sources:Amigo / QuickGO
Orthologau
	5864
	n/a
	ENSG00000105649
	n/a
	P20336
	n/a
	NM_002866
	n/a
	NP_002857; NP_002857.1
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB3A yw RAB3A a elwir hefyd yn H.sapiens ras-related Hrab3A protein a RAB3A, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.11.^[2]

Llyfryddiaeth

"Cholesterol content regulates acrosomal exocytosis by enhancing Rab3A plasma membrane association. ". Dev Biol. 2005. PMID 16099449.
"DNA variants in the human RAB3A gene are not associated with autism. ". Genes Brain Behav. 2004. PMID 15005721.
"3D structure generation, virtual screening and docking of human Ras-associated binding (Rab3A) protein involved in tumourigenesis. ". Mol Biol Rep. 2014. PMID 24652202.
"Membrane-permeant Rab3A triggers acrosomal exocytosis in living human sperm. ". FASEB J. 2007. PMID 17625073.
"Variants in the RAB3A gene are not associated with mental retardation in the Chinese population.". Neurosci Lett. 2006. PMID 16584842.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RAB3A - Cronfa NCBI

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[2]