RAB6A

RAB6A
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1YZQ, 2GIL, 3BBP, 3CWZ, 4DKX
Dynodwyr
Cyfenwau	RAB6A, RAB6, member RAS oncogene family
Dynodwyr allanol	OMIM: 179513 HomoloGene: 55697 GeneCards: RAB6A
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • protein domain specific binding; • GTP binding; • myosin V binding; • GO:0001948, GO:0016582 protein binding; • GO:0006184 GTPase activity;
Cydrannau o'r gell	• Golgi apparatus; • bilen; • endosome to plasma membrane transport vesicle; • trans-Golgi network; • extracellular exosome; • GO:0016023 cytoplasmic vesicle; • trans-Golgi network membrane; • cytosol; • endoplasmic reticulum membrane; • Golgi membrane; • Cellbilen; • secretory granule membrane;
Prosesau biolegol	• antigen processing and presentation; • early endosome to Golgi transport; • peptidyl-cysteine methylation; • protein localization to Golgi apparatus; • protein transport; • minus-end-directed organelle transport along microtubule; • GO:0022415 viral process; • vesicle-mediated transport; • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; • neutrophil degranulation; • GO:0015915 transport; • intracellular protein transport; • intra-Golgi vesicle-mediated transport; • Rab protein signal transduction; • retrograde transport, endosome to Golgi;
	Sources:Amigo / QuickGO
Orthologau
	5870
	n/a
	ENSG00000175582
	n/a
	P20340
	n/a
	NM_198896; NM_001243718; NM_001243719; NM_002869
	n/a
	NP_001230647; NP_001230648; NP_002860; NP_942599
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB6A yw RAB6A a elwir hefyd yn RAB6A, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q13.4.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAB6A.

RAB6

Llyfryddiaeth

"Rab and actomyosin-dependent fission of transport vesicles at the Golgi complex. ". Nat Cell Biol. 2010. PMID 20562865.
"Rab6 regulates transport and targeting of exocytotic carriers. ". Dev Cell. 2007. PMID 17681140.
"Targeting of the small GTPase Rab6A' by the Legionella pneumophila effector LidA. ". Infect Immun. 2013. PMID 23569112.
"Crystal structure of Rab6A'(Q72L) mutant reveals unexpected GDP/MgÂ²âº binding with opened GTP-binding domain. ". Biochem Biophys Res Commun. 2012. PMID 22750005.
"Rab6 is a modulator of the unfolded protein response: implications for Alzheimer's disease.". J Alzheimers Dis. 2012. PMID 22124028.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RAB6A - Cronfa NCBI

[1]

[2]