RAB8A

RAB8A
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3QBT, 3TNF, 4LHV, 4LHW, 4LHX, 4LHY, 4LHZ, 4LI0
Dynodwyr
Cyfenwau	RAB8A, MEL, RAB8, member RAS oncogene family
Dynodwyr allanol	OMIM: 165040 HomoloGene: 100934 GeneCards: RAB8A
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • GDP binding; • GTP binding; • myosin V binding; • GO:0001948, GO:0016582 protein binding; • protein kinase binding; • GO:0006184 GTPase activity;
Cydrannau o'r gell	• cytoplasm; • ciliary basal body; • recycling endosome; • cytosol; • endosome; • centrosome; • phagocytic vesicle membrane; • Golgi apparatus; • cell projection; • bilen; • GO:0097483, GO:0097481 postsynaptic density; • synaptic vesicle; • Golgi membrane; • cilium; • ciliary base; • soma; • dendrite; • phagocytic vesicle; • centriole; • extracellular exosome; • Cytosgerbwd; • GO:0016023 cytoplasmic vesicle; • GO:0005578 extracellular matrix; • Cellbilen; • trans-Golgi network transport vesicle; • trans-Golgi network membrane; • dendritic spine; • recycling endosome membrane; • non-motile cilium; • secretory granule membrane; • midbody; • synapse; • glutamatergic synapse;
Prosesau biolegol	• regulation of long-term neuronal synaptic plasticity; • regulation of protein transport; • axonogenesis; • vesicle docking involved in exocytosis; • protein secretion; • regulation of protein localization; • cell projection organization; • G2/M transition of mitotic cell cycle; • Golgi vesicle fusion to target membrane; • protein transport; • protein localization to plasma membrane; • cellular response to insulin stimulus; • cilium assembly; • ciliary basal body-plasma membrane docking; • neurotransmitter receptor transport to postsynaptic membrane; • regulation of autophagy; • autophagy; • post-translational protein modification; • regulation of exocytosis; • GO:0015915 transport; • intracellular protein transport; • Rab protein signal transduction; • neurotransmitter receptor transport, endosome to postsynaptic membrane; • vesicle-mediated transport in synapse;
	Sources:Amigo / QuickGO
Orthologau
	4218
	n/a
	ENSG00000167461
	n/a
	P61006
	n/a
	NM_005370
	n/a
	NP_005361; NP_005361.2
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAB8A yw RAB8A a elwir hefyd yn RAB8A, member RAS oncogene family, isoform CRA_a a RAB8A, member RAS oncogene family (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19p13.11.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAB8A.

MEL
RAB8

Llyfryddiaeth

"Endocytic turnover of Rab8 controls cell polarization. ". J Cell Sci. 2017. PMID 28137756.
"Protease-Resistant and Cell-Permeable Double-Stapled Peptides Targeting the Rab8a GTPase. ". ACS Chem Biol. 2016. PMID 27336832.
"Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes. ". FASEB J. 2015. PMID 26220176.
"RAB8A a new biomarker for endometrial cancer?". World J Surg Oncol. 2014. PMID 25477298.
"Rab8, a vesicular traffic regulator, is involved in dengue virus infection in HepG2 cells.". Intervirology. 2008. PMID 18724065.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RAB8A - Cronfa NCBI

[1]

[2]