RAD23A

RAD23A
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1DV0, 1F4I, 1IFY, 1OQY, 1P98, 1P9D, 1QZE, 1TP4, 2WYQ
Dynodwyr
Cyfenwau	RAD23A, HHR23A, HR23A, RAD23 homolog A, nucleotide excision repair protein
Dynodwyr allanol	OMIM: 600061 HomoloGene: 48322 GeneCards: RAD23A
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• single-stranded DNA binding; • ubiquitin-specific protease binding; • damaged DNA binding; • polyubiquitin modification-dependent protein binding; • GO:0001948, GO:0016582 protein binding; • kinase binding; • ubiquitin binding; • proteasome binding;
Cydrannau o'r gell	• proteasome complex; • nucleoplasm; • microtubule organizing center; • cytosol; • cnewyllyn cell; • cytoplasm; • intracellular membrane-bounded organelle; • GO:0009327 protein-containing complex;
Prosesau biolegol	• nucleotide-excision repair; • positive regulation of viral genome replication; • GO:0022415 viral process; • GO:0100026 DNA repair; • cellular response to DNA damage stimulus; • proteasome-mediated ubiquitin-dependent protein catabolic process; • regulation of proteasomal ubiquitin-dependent protein catabolic process; • protein deubiquitination; • protein destabilization; • positive regulation of proteasomal ubiquitin-dependent protein catabolic process; • positive regulation of cell cycle;
	Sources:Amigo / QuickGO
Orthologau
	5886
	n/a
	ENSG00000179262
	n/a
	P54725
	n/a
	NM_001270362; NM_001270363; NM_005053
	n/a
	NP_001257291; NP_001257292; NP_005044
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAD23A yw RAD23A a elwir hefyd yn UV excision repair protein RAD23 homolog A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19p13.13.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAD23A.

HR23A
HHR23A

Llyfryddiaeth

"Crystallization and preliminary X-ray diffraction studies of the ubiquitin-like (UbL) domain of the human homologue A of Rad23 (hHR23A) protein. ". Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID 19724136.
"Binding of polyubiquitin chains to ubiquitin-associated (UBA) domains of HHR23A. ". J Mol Biol. 2004. PMID 15321727.
"Human Rad23A plays a regulatory role in autophagy. ". Biochem Biophys Res Commun. 2016. PMID 27613096.
"Cisplatin transiently up-regulates hHR23 expression through enhanced translational efficiency in A549 adenocarcinoma cells. ". Toxicol Lett. 2011. PMID 21742020.
"The crystal structure of the ubiquitin-like (UbL) domain of human homologue A of Rad23 (hHR23A) protein.". Protein Eng Des Sel. 2011. PMID 21047872.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RAD23A - Cronfa NCBI

[1]

[2]