RAD23B

RAD23B
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1P1A, 1PVE, 1UEL
Dynodwyr
Cyfenwau	RAD23B, HHR23B, HR23B, P58, RAD23 homolog B, nucleotide excision repair protein
Dynodwyr allanol	OMIM: 600062 HomoloGene: 37704 GeneCards: RAD23B
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• single-stranded DNA binding; • damaged DNA binding; • polyubiquitin modification-dependent protein binding; • GO:0001948, GO:0016582 protein binding; • ubiquitin binding; • proteasome binding;
Cydrannau o'r gell	• XPC complex; • proteasome complex; • cnewyllyn cell; • nucleoplasm; • cytoplasm; • cytosol;
Prosesau biolegol	• cellular response to DNA damage stimulus; • nucleotide-excision repair; • global genome nucleotide-excision repair; • nucleotide-excision repair, DNA damage recognition; • spermatogenesis; • embryonic organ development; • proteasome-mediated ubiquitin-dependent protein catabolic process; • regulation of proteasomal ubiquitin-dependent protein catabolic process; • GO:0100026 DNA repair; • nucleotide-excision repair, preincision complex assembly; • protein folding; • protein deubiquitination; • cellular response to interleukin-7; • nucleotide-excision repair, DNA duplex unwinding;
	Sources:Amigo / QuickGO
Orthologau
	5887
	n/a
	ENSG00000119318
	n/a
	P54727; Q5W0S4
	n/a
	NM_002874; NM_001244713; NM_001244724
	n/a
	NP_001231642; NP_001231653; NP_002865
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAD23B yw RAD23B a elwir hefyd yn UV excision repair protein RAD23 homolog B a RAD23 homolog B, nucleotide excision repair protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q31.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAD23B.

P58
HR23B
HHR23B

Llyfryddiaeth

"Studies on the intracellular localization of hHR23B. ". Biochem Biophys Res Commun. 2005. PMID 16253613.
"Solution structure and backbone dynamics of the XPC-binding domain of the human DNA repair protein hHR23B. ". FEBS J. 2005. PMID 15885096.
"Identification and functional validation of RAD23B as a potential protein in human breast cancer progression. ". J Proteome Res. 2014. PMID 24897598.
"The association between RAD23B Ala249Val polymorphism and cancer susceptibility: evidence from a meta-analysis. ". PLoS One. 2014. PMID 24643114.
"Epigenetic therapy using belinostat for patients with unresectable hepatocellular carcinoma: a multicenter phase I/II study with biomarker and pharmacokinetic analysis of tumors from patients in the Mayo Phase II Consortium and the Cancer Therapeutics Research Group.". J Clin Oncol. 2012. PMID 22915658.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RAD23B - Cronfa NCBI

[1]

[2]