RAD9A

RAD9A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3A1J, 3G65, 3GGR
Dynodwyr
Cyfenwau	RAD9A, RAD9, RAD9 checkpoint clamp component A
Dynodwyr allanol	OMIM: 603761 HomoloGene: 32118 GeneCards: RAD9A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • SH3 domain binding • histone deacetylase binding • exodeoxyribonuclease III activity • GO:0001948, GO:0016582 protein binding • 3'-5' exonuclease activity • enzyme binding • nuclease activity • exonuclease activity • hydrolase activity • protein kinase binding Cydrannau o'r gell • cytoplasm • nucleoplasm • checkpoint clamp complex • cnewyllyn cell Prosesau biolegol • cell cycle checkpoint signaling • mitotic intra-S DNA damage checkpoint signaling • DNA damage checkpoint signaling • cellular response to DNA damage stimulus • DNA replication checkpoint signaling • positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage • cellular response to ionizing radiation • nucleic acid phosphodiester bond hydrolysis • GO:0100026 DNA repair • DNA replication • regulation of signal transduction by p53 class mediator Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5883	n/a
Ensembl	ENSG00000172613	n/a
UniProt	Q99638	n/a
RefSeq (mRNA)	NM_001243224 NM_004584	n/a
RefSeq (protein)	NP_001230153 NP_004575	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RAD9A yw RAD9A a elwir hefyd yn RAD9 checkpoint clamp component A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q13.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RAD9A.

• RAD9

Llyfryddiaeth

• "Cell cycle-dependent processing of DNA lesions controls localization of Rad9 to sites of genotoxic stress. ". Cell Cycle. 2009. PMID 19411845.
• "Localization of hRad9 in breast cancer. ". BMC Cancer. 2008. PMID 18616832.
• "The checkpoint clamp protein Rad9 facilitates DNA-end resection and prevents alternative non-homologous end joining. ". Cell Cycle. 2014. PMID 25485590.
• "Checkpoint protein Rad9 plays an important role in nucleotide excision repair. ". DNA Repair (Amst). 2013. PMID 23433811.
• "Reduced mRNA and protein expression of the genomic caretaker RAD9A in primary fibroblasts of individuals with childhood and independent second cancer.". PLoS One. 2011. PMID 21991345.

Cyfeiriadau

1. "Human PubMed Reference:".
2. RAD9A - Cronfa NCBI