RALA

RALA
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1UAD, 1ZC3, 1ZC4, 2A78, 2A9K, 2BOV
Dynodwyr
Cyfenwau	RALA, RAL, RALA Ras like proto-oncogene A, RAS like proto-oncogene A, HINCONS
Dynodwyr allanol	OMIM: 179550 HomoloGene: 3942 GeneCards: RALA
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• Edg-2 lysophosphatidic acid receptor binding; • nucleotide binding; • GDP binding; • myosin binding; • ATPase binding; • GTP binding; • GO:0001948, GO:0016582 protein binding; • GO:0006184 GTPase activity; • ubiquitin protein ligase binding;
Cydrannau o'r gell	• bilen; • focal adhesion; • myelin sheath; • Cellbilen; • endocytic vesicle; • cleavage furrow; • extracellular exosome; • cytoplasmic vesicle membrane; • cell surface; • Flemming body; • intracellular anatomical structure;
Prosesau biolegol	• actin cytoskeleton reorganization; • Cellraniad; • regulation of exocytosis; • chemotaxis; • neural tube closure; • membrane raft localization; • cell cycle; • membrane organization; • GO:0022415 viral process; • positive regulation of filopodium assembly; • GO:0072468 signal transduction; • exocytosis; • Ras protein signal transduction; • interleukin-12-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologau
	5898
	n/a
	ENSG00000006451
	n/a
	P11233
	n/a
	NM_005402
	n/a
	NP_005393
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RALA yw RALA a elwir hefyd yn Ras-related protein Ral-A a RAS like proto-oncogene a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7p14.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RALA.

RAL

Llyfryddiaeth

"Response to MLN8237 in pancreatic cancer is not dependent on RalA phosphorylation. ". Mol Cancer Ther. 2014. PMID 24222664.
"miR-181a post-transcriptionally downregulates oncogenic RalA and contributes to growth inhibition and apoptosis in chronic myelogenous leukemia (CML). ". PLoS One. 2012. PMID 22442671.
"RalA is overactivated in medulloblastoma. ". J Neurooncol. 2016. PMID 27566179.
"Evaluation and characterization of anti-RalA autoantibody as a potential serum biomarker in human prostate cancer. ". Oncotarget. 2016. PMID 27286458.
"Agonist-induced changes in RalA activities allows the prediction of the endocytosis of G protein-coupled receptors.". Biochim Biophys Acta. 2016. PMID 26477566.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RALA - Cronfa NCBI

[1]

[2]