RALB

RALB
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2KE5, 2KWI
Dynodwyr
Cyfenwau	RALB, RAS like proto-oncogene B
Dynodwyr allanol	OMIM: 179551 HomoloGene: 20632 GeneCards: RALB
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • GDP binding; • ATPase binding; • GTP binding; • GO:0001948, GO:0016582 protein binding; • GO:0006184 GTPase activity; • ubiquitin protein ligase binding;
Cydrannau o'r gell	• bilen; • Cellbilen; • autophagosome; • exocyst; • extracellular exosome; • intracellular anatomical structure; • midbody;
Prosesau biolegol	• positive regulation of protein phosphorylation; • positive regulation of autophagosome assembly; • cellular response to starvation; • negative regulation of protein binding; • positive regulation of protein serine/threonine kinase activity; • Cellraniad; • regulation of exocyst assembly; • cellular response to exogenous dsRNA; • cell cycle; • positive regulation of protein binding; • GO:0072468 signal transduction; • regulation of exocyst localization; • GO:0097285 apoptotic process; • Ras protein signal transduction;
	Sources:Amigo / QuickGO
Orthologau
	5899
	n/a
	ENSG00000144118
	n/a
	P11234
	n/a
	NM_002881; NM_001369400
	n/a
	NP_002872; NP_001356329
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RALB yw RALB a elwir hefyd yn RAS like proto-oncogene B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q14.2.^[2]

Llyfryddiaeth

"1H, 13C and 15N resonance assignments for the small G protein RalB in its active conformation. ". Biomol NMR Assign. 2007. PMID 19636851.
"Generation of antibodies specific for the RalA and RalB GTP-binding proteins and determination of their concentration and distribution in human platelets. ". Biochim Biophys Acta. 1996. PMID 8972729.
"Inhibition of Ral GTPases Using a Stapled Peptide Approach. ". J Biol Chem. 2016. PMID 27334922.
"Involvement of RalB in the effect of geranylgeranyltransferase I on glioma cell migration and invasion. ". Clin Transl Oncol. 2015. PMID 25573158.
"Phosphorylation of RalB is important for bladder cancer cell growth and metastasis.". Cancer Res. 2010. PMID 20940393.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RALB - Cronfa NCBI

[1]

[2]