RGS18

RGS18
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2DLV, 2JM5, 2OWI
Dynodwyr
Cyfenwau	RGS18, RGS13, regulator of G-protein signaling 18, regulator of G protein signaling 18
Dynodwyr allanol	OMIM: 607192 HomoloGene: 11281 GeneCards: RGS18
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0005097, GO:0005099, GO:0005100 GTPase activator activity; • GO:0001948, GO:0016582 protein binding; • GO:0006184 GTPase activity;
Cydrannau o'r gell	• cytoplasm; • Cellbilen;
Prosesau biolegol	• G protein-coupled receptor signaling pathway; • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity; • negative regulation of signal transduction; • regulation of G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologau
	64407
	n/a
	ENSG00000150681
	n/a
	Q9NS28
	n/a
	NM_130782
	n/a
	NP_570138
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RGS18 yw RGS18 a elwir hefyd yn Regulator of G protein signaling 18 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q31.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RGS18.

RGS13

Llyfryddiaeth

"Molecular cloning and characterization of a novel regulator of G-protein signaling from mouse hematopoietic stem cells. ". J Biol Chem. 2001. PMID 11042171.
"RGS18 is a myeloerythroid lineage-specific regulator of G-protein-signalling molecule highly expressed in megakaryocytes. ". Biochem J. 2001. PMID 11563974.
"Regulator of G-protein signaling 18 integrates activating and inhibitory signaling in platelets. ". Blood. 2012. PMID 22234696.
"Integrating energy calculations with functional assays to decipher the specificity of G protein-RGS protein interactions. ". Nat Struct Mol Biol. 2011. PMID 21685921.
"Selective expression of regulators of G-protein signaling (RGS) in the human central nervous system.". Brain Res Mol Brain Res. 2004. PMID 14992813.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RGS18 - Cronfa NCBI

[1]

[2]