RGS19

RGS19
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1CMZ
Dynodwyr
Cyfenwau	RGS19, GAIP, RGSGAIP, regulator of G-protein signaling 19, regulator of G protein signaling 19
Dynodwyr allanol	OMIM: 605071 HomoloGene: 23320 GeneCards: RGS19
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0005097, GO:0005099, GO:0005100 GTPase activator activity; • GO:0001948, GO:0016582 protein binding; • G-protein alpha-subunit binding; • GO:0006184 GTPase activity;
Cydrannau o'r gell	• cytoplasm; • Golgi apparatus; • bilen; • brush border; • heterotrimeric G-protein complex; • membrane raft; • clathrin-coated vesicle; • GO:0016023 cytoplasmic vesicle; • Cellbilen;
Prosesau biolegol	• G protein-coupled receptor signaling pathway; • small GTPase mediated signal transduction; • autophagy; • negative regulation of signal transduction; • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity; • response to ethanol;
	Sources:Amigo / QuickGO
Orthologau
	10287
	n/a
	ENSG00000171700
	n/a
	P49795
	n/a
	NM_001039467; NM_005873
	n/a
	NP_001034556; NP_005864
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RGS19 yw RGS19 a elwir hefyd yn Regulator of G protein signaling 19 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20q13.33.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RGS19.

GAIP
RGSGAIP

Llyfryddiaeth

"RGS19 stimulates cell proliferation by deregulating cell cycle control and enhancing Akt signaling. ". Cancer Lett. 2011. PMID 21705135.
"Solution structure of human GAIP (Galpha interacting protein): a regulator of G protein signaling. ". J Mol Biol. 1999. PMID 10452897.
"RGS19 converts iron deprivation stress into a growth-inhibitory signal. ". Biochem Biophys Res Commun. 2015. PMID 26116529.
"5-HT1A receptor-mediated phosphorylation of extracellular signal-regulated kinases (ERK1/2) is modulated by regulator of G protein signaling protein 19. ". Cell Signal. 2014. PMID 24793302.
"Elevated expression of RGS19 impairs the responsiveness of stress-activated protein kinases to serum.". Mol Cell Biochem. 2012. PMID 22045062.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RGS19 - Cronfa NCBI

[1]

[2]