RNH1

RNH1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1Z7X, 1A4Y, 2BEX, 2Q4G
Dynodwyr
Cyfenwau	RNH1, RAI, RNH, ribonuclease/angiogenin inhibitor 1
Dynodwyr allanol	OMIM: 173320 HomoloGene: 2204 GeneCards: RNH1
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• ribonuclease inhibitor activity; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• angiogenin-PRI complex; • extracellular exosome; • nucleoplasm; • cytoplasm; • cytosol;
Prosesau biolegol	• regulation of angiogenesis; • mRNA catabolic process; • GO:0048553 negative regulation of catalytic activity;
	Sources:Amigo / QuickGO
Orthologau
	6050
	n/a
	ENSG00000276230; ENSG00000023191
	n/a
	P13489
	n/a
NM_002939; NM_203383; NM_203384; NM_203385; NM_203386;
	NM_203387; NM_203388; NM_203389
	n/a
NP_002930; NP_976317; NP_976318; NP_976319; NP_976320;
	NP_976321; NP_976322; NP_976323
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RNH1 yw RNH1 a elwir hefyd yn Ribonuclease/angiogenin inhibitor 1 a Ribonuclease inhibitor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11p15.5.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RNH1.

RAI
RNH

Llyfryddiaeth

"Knockdown of ribonuclease inhibitor expression with siRNA in non-invasive bladder cancer cell line BIU-87 promotes growth and metastasis potentials. ". Mol Cell Biochem. 2011. PMID 21125316.
"Interaction of onconase with the human ribonuclease inhibitor protein. ". Biochem Biophys Res Commun. 2008. PMID 18930025.
"Down-regulating ribonuclease inhibitor enhances metastasis of bladder cancer cells through regulating epithelial-mesenchymal transition and ILK signaling pathway. ". Exp Mol Pathol. 2014. PMID 24768914.
"RNH1 regulation of reactive oxygen species contributes to histone deacetylase inhibitor resistance in gastric cancer cells. ". Oncogene. 2014. PMID 23584480.
"The ribonuclease/angiogenin inhibitor is also present in mitochondria and nuclei.". FEBS Lett. 2011. PMID 21276451.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RNH1 - Cronfa NCBI

[1]

[2]