RPL12

RPL12
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	4V6X, 5AJ0, 3J92, 4V5Z, 5A8L
Dynodwyr
Cyfenwau	RPL12, L12, ribosomal protein L12
Dynodwyr allanol	OMIM: 180475 HomoloGene: 128047 GeneCards: RPL12
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • structural constituent of ribosome; • rRNA binding; • RNA binding; • large ribosomal subunit rRNA binding;
Cydrannau o'r gell	• cytosol; • extracellular exosome; • bilen; • cytosolic large ribosomal subunit; • focal adhesion; • ribosom; • GO:0005578 extracellular matrix; • cnewyllyn cell; • nucleolus; • cytoplasm; • GO:0097483, GO:0097481 postsynaptic density; • large ribosomal subunit;
Prosesau biolegol	• translational initiation; • SRP-dependent cotranslational protein targeting to membrane; • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; • ribosomal large subunit assembly; • viral transcription; • protein biosynthesis; • rRNA processing;
	Sources:Amigo / QuickGO
Orthologau
	6136
	n/a
	ENSG00000197958
	n/a
	P30050
	n/a
	NM_000976
	n/a
	NP_000967
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RPL12 yw RPL12 a elwir hefyd yn Ribosomal protein L12 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9q33.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RPL12.

L12

Llyfryddiaeth

"Palmitoylated calnexin is a key component of the ribosome-translocon complex. ". EMBO J. 2012. PMID 22314232.
"Mitochondrial ribosomal protein L12 selectively associates with human mitochondrial RNA polymerase to activate transcription. ". Proc Natl Acad Sci U S A. 2011. PMID 22003127.
"The primary structure of human ribosomal protein L12. ". Nucleic Acids Res. 1993. PMID 8441690.
"Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect. ". PLoS Biol. 2016. PMID 27168400.
"Binding of mammalian ribosomal protein complex P0.P1.P2 and protein L12 to the GTPase-associated domain of 28 S ribosomal RNA and effect on the accessibility to anti-28 S RNA autoantibody.". J Biol Chem. 1997. PMID 9013569.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RPL12 - Cronfa NCBI

[1]

[2]