RRAS

RRAS
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2FN4
Dynodwyr
Cyfenwau	RRAS, related RAS viral (r-ras) oncogene homolog, R-Ras, RAS related
Dynodwyr allanol	OMIM: 165090 HomoloGene: 4565 GeneCards: RRAS
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • GDP binding; • GO:0032403 protein-containing complex binding; • GTP binding; • GO:0001948, GO:0016582 protein binding; • GO:0006184 GTPase activity;
Cydrannau o'r gell	• bilen; • focal adhesion; • Cellbilen; • extracellular exosome; • intracellular anatomical structure;
Prosesau biolegol	• positive regulation of angiogenesis; • negative regulation of cell migration; • regulation of protein kinase B signaling; • regulation of ERK1 and ERK2 cascade; • leukocyte differentiation; • Ras protein signal transduction; • face morphogenesis; • GO:0072468 signal transduction;
	Sources:Amigo / QuickGO
Orthologau
	6237
	n/a
	ENSG00000126458
	n/a
	P10301
	n/a
	NM_006270
	n/a
	NP_006261
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RRAS yw RRAS a elwir hefyd yn RAS related (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19q13.33.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RRAS.

R-Ras

Llyfryddiaeth

"Promoter cloning and characterization of the anti-vascular proliferation gene, R-ras: role of Ets- and Sp-binding motifs. ". J Biol Chem. 2009. PMID 19011236.
"The R-Ras GTPase mediates cross talk between estrogen and insulin signaling in breast cancer cells. ". Mol Cell Biol. 2006. PMID 16914723.
"Negative association of R-Ras activation and breast cancer development. ". Oncol Rep. 2014. PMID 24700169.
"A polymorphism linked to RRAS, SCAF1, IRF3 and BCL2L12 genes is associated with cirrhosis in hepatitis C virus carriers. ". Liver Int. 2014. PMID 24131527.
"RRAS: A key regulator and an important prognostic biomarker in biliary atresia.". World J Gastroenterol. 2011. PMID 21390152.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] RRAS - Cronfa NCBI

[1]

[2]