RXRB |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Protein_RXRB_PDB_1by4.png/250px-Protein_RXRB_PDB_1by4.png) |
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Dynodwyr |
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Cyfenwau | RXRB, DAUDI6, H-2RIIBP, NR2B2, RCoR-1, Retinoid X receptor beta, RXRbeta, RXR-beta |
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Dynodwyr allanol | OMIM: 180246 HomoloGene: 7923 GeneCards: RXRB |
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Ontoleg y genyn |
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Gweithrediad moleciwlaidd | • DNA binding • sequence-specific DNA binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001105 transcription coactivator activity • zinc ion binding • metal ion binding • steroid hormone receptor activity • GO:0038050, GO:0004886, GO:0038051 nuclear receptor activity • GO:0001948, GO:0016582 protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
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Cydrannau o'r gell | • nucleoplasm • cnewyllyn cell
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Prosesau biolegol | • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • retinoic acid receptor signaling pathway • transcription initiation from RNA polymerase II promoter • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • steroid hormone mediated signaling pathway • intracellular receptor signaling pathway
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Sources:Amigo / QuickGO |
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Orthologau |
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Species | Bod dynol | Llygoden |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Lleoliad (UCSC) | n/a | n/a |
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PubMed search | [1] | n/a |
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Wicidata |
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Protein sy'n cael ei godio yn y corff dynol gan y genyn RXRB yw RXRB a elwir hefyd yn Retinoid X nuclear receptor beta (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.32.[2]
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RXRB.
- NR2B2
- DAUDI6
- RCoR-1
- H-2RIIBP
- "Mapping of RXRB to human chromosome 6p21.3. ". Ann Hum Genet. 1993. PMID 8257090.
- "The human cDNA sequence homologous to the mouse MHC class I promoter-binding protein gene contains four additional codons in lymphocytes. ". Mamm Genome. 1992. PMID 1514958.
- "Retinoid X receptor beta polymorphisms do not explain functional differences in vitamins D and A response in Antineutrophil cytoplasmic antibody associated vasculitis patients. ". Autoimmunity. 2009. PMID 19811264.
- "Age-related change in the retinoid X receptor beta gene expression in peripheral blood mononuclear cells of healthy volunteers: effect of 13-cis retinoic acid supplementation. ". Mech Ageing Dev. 2007. PMID 17916375.
- "The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12.". J Biol Chem. 2002. PMID 11782480.