SART3

SART3
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2DO4, 5JJW, 5JJX, 5CTT, 5CTR, 5JPZ, 5CTQ
Dynodwyr
Cyfenwau	SART3, DSAP1, P100, RP11-13G14, TIP110, p110, p110(nrb), squamous cell carcinoma antigen recognized by T-cells 3, squamous cell carcinoma antigen recognized by T cells 3, spliceosome associated factor 3, U4/U6 recycling protein
Dynodwyr allanol	OMIM: 611684 HomoloGene: 40977 GeneCards: SART3
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• U6atac snRNA binding; • GO:0031493 histone binding; • U4 snRNA binding; • GO:0001948, GO:0016582 protein binding; • nucleic acid binding; • ubiquitin-specific protease binding; • U6 snRNA binding; • RNA binding;
Cydrannau o'r gell	• cytoplasm; • Cajal body; • nuclear speck; • U4/U6 x U5 tri-snRNP complex; • nucleoplasm; • U4/U6 snRNP; • U6atac snRNP; • U4atac/U6atac snRNP; • cnewyllyn cell; • ASAP complex;
Prosesau biolegol	• mRNA splicing, via spliceosome; • nucleosome assembly; • GO:0033168, GO:0036404, GO:1902360 RNA processing; • spliceosomal tri-snRNP complex assembly; • homeostasis of number of cells; • positive regulation of histone deubiquitination; • hematopoietic stem cell proliferation; • mRNA processing; • spliceosomal snRNP assembly; • GO:0000767 cell morphogenesis; • RNA splicing; • regulation of gene expression; • regulation of alternative mRNA splicing, via spliceosome;
	Sources:Amigo / QuickGO
Orthologau
	9733
	n/a
	ENSG00000075856
	n/a
	Q15020
	n/a
	NM_014706
	n/a
	NP_055521
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SART3 yw SART3 a elwir hefyd yn Squamous cell carcinoma antigen recognized by T-cells 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q23.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SART3.

P100
p110
DSAP1
TIP110
p110(nrb)
RP11-13G14

Llyfryddiaeth

"Structural Basis of the Recruitment of Ubiquitin-specific Protease USP15 by Spliceosome Recycling Factor SART3. ". J Biol Chem. 2016. PMID 27255711.
"Tip110 interacts with YB-1 and regulates each other's function. ". BMC Mol Biol. 2013. PMID 23822148.
"Tip110 maintains expression of pluripotent factors in and pluripotency of human embryonic stem cells. ". Stem Cells Dev. 2012. PMID 22132941.
"3'-cyclic phosphorylation of U6 snRNA leads to recruitment of recycling factor p110 through LSm proteins. ". RNA. 2008. PMID 18567812.
"A mutation in SART3 gene in a Chinese pedigree with disseminated superficial actinic porokeratosis.". Br J Dermatol. 2005. PMID 15840095.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] SART3 - Cronfa NCBI

[1]

[2]