SERPINB3

SERPINB3
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2ZV6, 4ZK0, 4ZK3
Dynodwyr
Cyfenwau	SERPINB3, HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, T4-A, SSCA1, serpin family B member 3
Dynodwyr allanol	OMIM: 600517 HomoloGene: 130559 GeneCards: SERPINB3
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• virus receptor activity; • protease binding; • cysteine-type endopeptidase inhibitor activity; • peptidase inhibitor activity; • serine-type endopeptidase inhibitor activity;
Cydrannau o'r gell	• cnewyllyn cell; • fesigl; • GO:0016023 cytoplasmic vesicle; • extracellular exosome; • cytoplasm; • extracellular region; • extracellular space; • azurophil granule lumen;
Prosesau biolegol	• paracrine signaling; • positive regulation of cell population proliferation; • autocrine signaling; • GO:0048553 negative regulation of catalytic activity; • negative regulation of JUN kinase activity; • positive regulation of endopeptidase activity; • positive regulation of epithelial to mesenchymal transition; • negative regulation of proteolysis; • negative regulation of endopeptidase activity; • positive regulation of cell migration; • viral entry into host cell; • negative regulation of peptidase activity; • neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologau
	6317
	n/a
	ENSG00000057149
	n/a
	P29508
	n/a
	NM_006919
	n/a
	NP_008850
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SERPINB3 yw SERPINB3 a elwir hefyd yn Serpin family B member 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 18, band 18q21.33.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SERPINB3.

SCC
T4-A
SCCA1
SSCA1
SCCA-1
HsT1196
SCCA-PD

Llyfryddiaeth

"Squamous cell carcinoma antigen in hepatocellular carcinoma: Ready for the prime time?". Clin Chim Acta. 2015. PMID 25840050.
"Prognostic significance of serum squamous cell carcinoma antigen in patients with head and neck cancer. ". Acta Otolaryngol. 2015. PMID 25622661.
"The Correlation Between the Serum Squamous Carcinoma Antigen and the Prognosis of Recurrent Cervical Squamous Carcinoma. ". J Clin Lab Anal. 2017. PMID 27435426.
"Evaluation of vaginal fluid squamous cell carcinoma antigen test in diagnosis of premature rupture of membranes. ". J Matern Fetal Neonatal Med. 2017. PMID 27095020.
"Squamous cell carcinoma antigen as a diagnostic marker of nasal inverted papilloma.". Am J Rhinol Allergy. 2016. PMID 26877539.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] SERPINB3 - Cronfa NCBI

[1]

[2]