SERPINF1

SERPINF1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1IMV
Dynodwyr
Cyfenwau	SERPINF1, EPC-1, OI12, OI6, PEDF, PIG35, serpin family F member 1
Dynodwyr allanol	OMIM: 172860 HomoloGene: 1965 GeneCards: SERPINF1
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • serine-type endopeptidase inhibitor activity;
Cydrannau o'r gell	• GO:0005578 extracellular matrix; • melanosome; • extracellular region; • basement membrane; • axon; • soma; • perinuclear region of cytoplasm; • axon hillock; • extracellular exosome; • extracellular space; • collagen-containing extracellular matrix;
Prosesau biolegol	• cellular response to retinoic acid; • kidney development; • GO:0010260 heneiddio; • response to arsenic-containing substance; • negative regulation of gene expression; • cellular response to dexamethasone stimulus; • negative regulation of endothelial cell migration; • multicellular organism development; • cellular response to cobalt ion; • retina development in camera-type eye; • short-term memory; • negative regulation of epithelial cell proliferation involved in prostate gland development; • positive regulation of neuron projection development; • ovulation cycle; • negative regulation of angiogenesis; • cell population proliferation; • negative regulation of inflammatory response; • cellular response to glucose stimulus; • response to acidic pH; • negative regulation of neuron death; • negative regulation of endopeptidase activity; • positive regulation of neurogenesis;
	Sources:Amigo / QuickGO
Orthologau
	5176
	n/a
	ENSG00000132386; ENSG00000282307
	n/a
	P36955
	n/a
	NM_002615; NM_001329903; NM_001329904; NM_001329905
	n/a
	NP_001316832; NP_001316833; NP_001316834; NP_002606
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SERPINF1 yw SERPINF1 a elwir hefyd yn Pigment epithelium-derived factor a Serpin family F member 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17p13.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SERPINF1.

OI6
OI12
PEDF
EPC-1
PIG35

Llyfryddiaeth

"Circulating level of pigment epithelium-derived factor is associated with vascular function and structure: A cross-sectional study. ". Int J Cardiol. 2016. PMID 27716557.
"Downregulation of pigment epithelium-derived factor is associated with increased epithelial-mesenchymal transition in bladder cancer. ". Panminerva Med. 2017. PMID 27644257.
"Activation of Complement by Pigment Epithelium-Derived Factor in Rheumatoid Arthritis. ". J Immunol. 2017. PMID 28637898.
"PEDF Is Associated with the Termination of Chondrocyte Phenotype and Catabolism of Cartilage Tissue. ". Biomed Res Int. 2017. PMID 28191465.
"Pigment epithelium-derived factor alleviates endothelial injury by inhibiting Wnt/β-catenin pathway.". Lipids Health Dis. 2017. PMID 28173817.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] SERPINF1 - Cronfa NCBI

[1]

[2]