SNAP23

SNAP23
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1NHL, 3ZUS
Dynodwyr
Cyfenwau	SNAP23, HsT17016, SNAP-23, SNAP23A, SNAP23B, synaptosome associated protein 23kDa, synaptosome associated protein 23
Dynodwyr allanol	OMIM: 602534 HomoloGene: 37857 GeneCards: SNAP23
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• SNAP receptor activity; • GO:0001948, GO:0016582 protein binding; • syntaxin binding;
Cydrannau o'r gell	• cytoplasm; • bilen; • focal adhesion; • Cellbilen; • synapse; • nucleoplasm; • cell junction; • SNARE complex; • azurophil granule; • specific granule; • neuron projection; • extracellular exosome; • presynapse; • mast cell granule; • phagocytic vesicle membrane; • specific granule membrane; • tertiary granule membrane;
Prosesau biolegol	• histamine secretion by mast cell; • vesicle targeting; • synaptic vesicle fusion to presynaptic active zone membrane; • membrane fusion; • post-Golgi vesicle-mediated transport; • synaptic vesicle priming; • protein transport; • antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; • neutrophil degranulation; • GO:0015915 transport; • exocytosis; • vesicle fusion;
	Sources:Amigo / QuickGO
Orthologau
	8773
	n/a
	ENSG00000092531
	n/a
	O00161
	n/a
	NM_003825; NM_130798
	n/a
	NP_003816; NP_570710
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SNAP23 yw SNAP23 a elwir hefyd yn Synaptosomal-associated protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q15.1-q15.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SNAP23.

SNAP-23
SNAP23A
SNAP23B
HsT17016

Llyfryddiaeth

"Granule exocytosis contributes to priming and activation of the human neutrophil respiratory burst. ". J Immunol. 2011. PMID 21642540.
"Effect of dominant negative SNAP-23 expression on platelet function. ". J Thromb Haemost. 2008. PMID 18665925.
"SNAP23 promotes the malignant process of ovarian cancer. ". J Ovarian Res. 2016. PMID 27855700.
"Immunofluorescence microscopy of SNAP23 in human skeletal muscle reveals colocalization with plasma membrane, lipid droplets, and mitochondria. ". Physiol Rep. 2016. PMID 26733245.
"Synaptic vesicle-like lipidome of human cytomegalovirus virions reveals a role for SNARE machinery in virion egress.". Proc Natl Acad Sci U S A. 2011. PMID 21768361.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] SNAP23 - Cronfa NCBI

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[2]