SNX17

SNX17
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3FOG, 3LUI, 4GXB, 4TKN
Dynodwyr
Cyfenwau	SNX17, sorting nexin 17
Dynodwyr allanol	OMIM: 605963 HomoloGene: 8838 GeneCards: SNX17
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• low-density lipoprotein particle receptor binding; • protein C-terminus binding; • GO:0001948, GO:0016582 protein binding; • phosphatidylinositol binding; • signaling receptor binding; • lipid binding;
Cydrannau o'r gell	• cytosol; • endosome; • Golgi apparatus; • bilen; • intracellular membrane-bounded organelle; • early endosome; • endosome membrane; • cytoplasmic vesicle membrane; • cytoplasm; • GO:0016023 cytoplasmic vesicle; • GO:0009327 protein-containing complex;
Prosesau biolegol	• regulation of endocytosis; • cardiac septum development; • cholesterol catabolic process; • receptor-mediated endocytosis; • coronary vasculature development; • endosomal transport; • aorta development; • protein transport; • GO:0072468 signal transduction; • intracellular protein transport; • endocytic recycling;
	Sources:Amigo / QuickGO
Orthologau
	9784
	n/a
	ENSG00000115234
	n/a
	Q15036
	n/a
	NM_001267059; NM_001267060; NM_001267061; NM_014748
	n/a
	NP_001253988; NP_001253989; NP_001253990; NP_055563
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SNX17 yw SNX17 a elwir hefyd yn Sorting nexin 17 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p23.3.^[2]

Llyfryddiaeth

"Human papillomavirus L2 facilitates viral escape from late endosomes via sorting nexin 17. ". Traffic. 2012. PMID 22151726.
"Adaptor protein sorting nexin 17 interacts with the scavenger receptor FEEL-1/stabilin-1 and modulates its expression on the cell surface. ". Biochim Biophys Acta. 2010. PMID 20226821.
"SNX17 affects T cell activation by regulating TCR and integrin recycling. ". J Immunol. 2015. PMID 25825439.
"Sorting nexin 17 regulates ApoER2 recycling and reelin signaling. ". PLoS One. 2014. PMID 24705369.
"SNX17 facilitates infection with diverse papillomavirus types.". J Virol. 2013. PMID 23115288.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] SNX17 - Cronfa NCBI

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[2]