SNX9

SNX9
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2RAI, 2RAJ, 2RAK, 3DYT, 3DYU, 3LGE
Dynodwyr
Cyfenwau	SNX9, SDP1, SH3PX1, SH3PXD3A, WISP, sorting nexin 9
Dynodwyr allanol	OMIM: 605952 HomoloGene: 49454 GeneCards: SNX9
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• protein homodimerization activity; • Arp2/3 complex binding; • 1-phosphatidylinositol binding; • GO:0001948, GO:0016582 protein binding; • phosphatidylinositol binding; • ubiquitin protein ligase binding; • lipid binding; • cadherin binding; • identical protein binding;
Cydrannau o'r gell	• cytoplasm; • Golgi apparatus; • cell projection; • bilen; • ruffle; • extrinsic component of cytoplasmic side of plasma membrane; • Cellbilen; • trans-Golgi network; • extracellular exosome; • cytoplasmic vesicle membrane; • clathrin-coated vesicle; • cytosol; • GO:0016023 cytoplasmic vesicle; • cuticular plate;
Prosesau biolegol	• endocytosis; • cleavage furrow formation; • mitotic cytokinesis; • positive regulation of membrane protein ectodomain proteolysis; • receptor-mediated endocytosis; • plasma membrane tubulation; • Cellraniad; • endosomal transport; • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity; • positive regulation of protein oligomerization; • protein transport; • lipid tube assembly; • cell cycle; • intracellular protein transport; • positive regulation of protein kinase activity; • membrane organization; • GO:0007067 Mitosis; • GO:0015915 transport; • positive regulation of actin filament polymerization;
	Sources:Amigo / QuickGO
Orthologau
	51429
	n/a
	ENSG00000130340
	n/a
	Q9Y5X1
	n/a
	NM_016224
	n/a
	NP_057308
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SNX9 yw SNX9 a elwir hefyd yn Sorting nexin 9 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6q25.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SNX9.

SDP1
WISP
SH3PX1
SH3PXD3A

Llyfryddiaeth

"E. coli secreted protein F promotes EPEC invasion of intestinal epithelial cells via an SNX9-dependent mechanism. ". Cell Microbiol. 2010. PMID 20088948.
"SNX9 - a prelude to vesicle release. ". J Cell Sci. 2009. PMID 19092055.
"Sorting nexin 9 negatively regulates invadopodia formation and function in cancer cells. ". J Cell Sci. 2016. PMID 27278018.
"Impaired SNX9 Expression in Immune Cells during Chronic Inflammation: Prognostic and Diagnostic Implications. ". J Immunol. 2016. PMID 26608909.
"The unique mechanism of SNX9 BAR domain for inducing membrane tubulation.". Mol Cells. 2014. PMID 25256216.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] SNX9 - Cronfa NCBI

[1]

[2]