SOX14

SOX14
Dynodwyr
Cyfenwau	SOX14, SOX28, SRY-box 14, SRY-box transcription factor 14
Dynodwyr allanol	OMIM: 604747 HomoloGene: 31224 GeneCards: SOX14
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• sequence-specific DNA binding; • DNA binding; • chromatin binding; • GO:0001948, GO:0016582 protein binding; • protein heterodimerization activity; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Cydrannau o'r gell	• cnewyllyn cell; • cydran cellog;
Prosesau biolegol	• regulation of neuron migration; • GO:0045996 negative regulation of transcription, DNA-templated; • GO:0009373 regulation of transcription, DNA-templated; • GO:1901227 negative regulation of transcription by RNA polymerase II; • transcription, DNA-templated; • nervous system development; • golwg; • entrainment of circadian clock; • cell differentiation;
	Sources:Amigo / QuickGO
Orthologau
	8403
	n/a
	ENSG00000168875
	n/a
	O95416
	n/a
	NM_004189
	n/a
	NP_004180
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SOX14 yw SOX14 a elwir hefyd yn SRY-box 14 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3q22.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SOX14.

SOX28

Llyfryddiaeth

"SOX14 is a candidate gene for limb defects associated with BPES and Möbius syndrome. ". Hum Genet. 2000. PMID 10798354.
"The isolation and high-resolution chromosomal mapping of human SOX14 and SOX21; two members of the SOX gene family related to SOX1, SOX2, and SOX3. ". Mamm Genome. 1999. PMID 10441749.
"SOX14 promotes proliferation and invasion of cervical cancer cells through Wnt/β-catenin pathway. ". Int J Clin Exp Pathol. 2015. PMID 25973056.
"Characterisation and mapping of the human SOX14 gene. ". Cytogenet Cell Genet. 1998. PMID 9925951.
"Fine mapping of the neurally expressed gene SOX14 to human 3q23, relative to three congenital diseases.". Hum Genet. 2000. PMID 10830911.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] SOX14 - Cronfa NCBI

[1]

[2]