STK24

STK24
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3A7F, 3A7G, 3A7H, 3A7I, 3A7J, 3CKW, 3CKX, 3ZHP, 4O27, 4QML, 4QMM, 4QMN, 4QMO, 4QMP, 4QMQ, 4QMS, 4QMT, 4QMU, 4QMV, 4QMW, 4QMX, 4QMY, 4QMZ, 4QO9, 4U8Z, 4W8D, 4W8E, 4QNA
Dynodwyr
Cyfenwau	STK24, HEL-S-95, MST3, MST3B, STE20, STK3, serine/threonine kinase 24
Dynodwyr allanol	OMIM: 604984 HomoloGene: 20793 GeneCards: STK24
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• transferase activity; • nucleotide binding; • metal ion binding; • kinase activity; • GO:0001948, GO:0016582 protein binding; • ATP binding; • protein kinase activity; • protein serine/threonine kinase activity; • cadherin binding; • MAP kinase kinase kinase kinase activity;
Cydrannau o'r gell	• bilen; • nucleoplasm; • nucleolus; • extracellular exosome; • cnewyllyn cell; • cytosol; • cytoplasm; • Golgi apparatus;
Prosesau biolegol	• intrinsic apoptotic signaling pathway in response to oxidative stress; • regulation of axon regeneration; • phosphorylation; • negative regulation of cell migration; • response to hydrogen peroxide; • GO:0072468 signal transduction; • GO:0097285 apoptotic process; • protein phosphorylation; • execution phase of apoptosis; • cellular response to starvation; • protein autophosphorylation; • MAPK cascade; • regulation of mitotic cell cycle; • stress-activated protein kinase signaling cascade; • regulation of apoptotic process; • neuron projection morphogenesis; • activation of protein kinase activity;
	Sources:Amigo / QuickGO
Orthologau
	8428
	n/a
	ENSG00000102572
	n/a
	Q9Y6E0; Q5JV99
	n/a
	NM_001032296; NM_001286649; NM_003576
	n/a
	NP_001027467; NP_001273578; NP_003567
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn STK24 yw STK24 a elwir hefyd yn Serine/threonine-protein kinase 24 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 13, band 13q32.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn STK24.

MST3
STK3
MST3B
STE20
HEL-S-95

Llyfryddiaeth

"Mammalian Ste20-like protein kinase 3 mediates trophoblast apoptosis in spontaneous delivery. ". Apoptosis. 2008. PMID 18040775.
"Zinc ion acts as a cofactor for serine/threonine kinase MST3 and has a distinct role in autophosphorylation of MST3. ". J Inorg Biochem. 2005. PMID 15917084.
"Mammalian Ste20-like protein kinase 3 plays a role in hypoxia-induced apoptosis of trophoblast cell line 3A-sub-E. ". Int J Biochem Cell Biol. 2011. PMID 21277991.
"Structures of human MST3 kinase in complex with adenine, ADP and Mn2+. ". Acta Crystallogr D Biol Crystallogr. 2010. PMID 20124694.
"Mammalian Ste20-like protein kinase 3 induces a caspase-independent apoptotic pathway.". Int J Biochem Cell Biol. 2010. PMID 19782762.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] STK24 - Cronfa NCBI

[1]

[2]