TREM1

TREM1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1Q8M, 1SMO
Dynodwyr
Cyfenwau	TREM1, CD354, TREM-1, triggering receptor expressed on myeloid cells 1
Dynodwyr allanol	OMIM: 605085 HomoloGene: 10243 GeneCards: TREM1
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• scaffold protein binding; • signaling receptor activity;
Cydrannau o'r gell	• integral component of membrane; • bilen; • Cellbilen; • extracellular region; • intracellular anatomical structure;
Prosesau biolegol	• GO:0007243 intracellular signal transduction; • humoral immune response; • regulation of immune response; • innate immune response; • leukocyte migration; • acute inflammatory response;
	Sources:Amigo / QuickGO
Orthologau
	54210
	n/a
	ENSG00000124731
	n/a
	Q9NP99
	n/a
	NM_001242589; NM_001242590; NM_018643
	n/a
	NP_001229518; NP_001229519; NP_061113
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TREM1 yw TREM1 a elwir hefyd yn Triggering receptor expressed on myeloid cells 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TREM1.

CD354
TREM-1

Llyfryddiaeth

"Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway. ". Biochem Biophys Res Commun. 2017. PMID 27932245.
"Significance of soluble triggering receptor expressed on myeloid cells-1 elevation in patients admitted to the intensive care unit with sepsis. ". BMC Infect Dis. 2016. PMID 27729010.
"TREM-1 SNP rs2234246 regulates TREM-1 protein and mRNA levels and is associated with plasma levels of L-selectin. ". PLoS One. 2017. PMID 28771614.
"Urine TREM-1 as a marker of urinary tract infection in children. ". J Int Med Res. 2017. PMID 28367708.
"Increased expression of triggering receptor expressed on myeloid cells-1 in the population with obesity and insulin resistance.". Obesity (Silver Spring). 2017. PMID 28111922.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] TREM1 - Cronfa NCBI

[1]

[2]