TRPV2

TRPV2
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2F37
Dynodwyr
Cyfenwau	TRPV2, VRL, VRL-1, VRL1, transient receptor potential cation channel subfamily V member 2
Dynodwyr allanol	OMIM: 606676 HomoloGene: 7993 GeneCards: TRPV2
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• ion transmembrane transporter activity; • ion channel activity; • cation channel activity; • calcium channel activity;
Cydrannau o'r gell	• cytoplasm; • integral component of membrane; • cell body; • bilen; • melanosome; • Cellbilen; • growth cone membrane; • axonal growth cone; • integral component of plasma membrane; • intracellular anatomical structure; • cell surface; • axon;
Prosesau biolegol	• sensory perception; • response to heat; • cludo ïon; • positive regulation of calcium ion import; • calcium ion transmembrane transport; • positive regulation of axon extension; • response to temperature stimulus; • calcium ion transport; • transmembrane transport; • positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologau
	51393
	n/a
	ENSG00000187688
	n/a
	Q9Y5S1
	n/a
	NM_016113
	n/a
	NP_057197
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TRPV2 yw TRPV2 a elwir hefyd yn Transient receptor potential cation channel subfamily V member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17p11.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TRPV2.

VRL
VRL1
VRL-1

Llyfryddiaeth

"Rational design and validation of a vanilloid-sensitive TRPV2 ion channel. ". Proc Natl Acad Sci U S A. 2016. PMID 27298359.
"Nerve Growth Factor Regulates Transient Receptor Potential Vanilloid 2 via Extracellular Signal-Regulated Kinase Signaling To Enhance Neurite Outgrowth in Developing Neurons. ". Mol Cell Biol. 2015. PMID 26416880.
"Mechanosensitive CaÂ²âº-permeable channels in human leukemic cells: pharmacological and molecular evidence for TRPV2. ". Biochim Biophys Acta. 2015. PMID 25268680.
"Advances in transient receptor potential vanilloid-2 channel expression and function in tumor growth and progression. ". Curr Protein Pept Sci. 2014. PMID 25001513.
"Overexpression of transient receptor potential vanilloid 2 is associated with poor prognosis in patients with esophageal squamous cell carcinoma.". Med Oncol. 2014. PMID 24878697.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] TRPV2 - Cronfa NCBI

[1]

[2]