UBE2D1

UBE2D1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2C4P, 2YHO, 3OJ4, 3PTF, 4AP4, 4QPL, 5FER
Dynodwyr
Cyfenwau	UBE2D1, E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A, ubiquitin conjugating enzyme E2 D1
Dynodwyr allanol	OMIM: 602961 HomoloGene: 20714 GeneCards: UBE2D1
EC number	2.3.2.24
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • ubiquitin conjugating enzyme activity; • ATP binding; • GO:0001948, GO:0016582 protein binding; • GO:0050372 ubiquitin-protein transferase activity; • ubiquitin protein ligase binding;
Cydrannau o'r gell	• cytoplasm; • nucleoplasm; • cytosol; • ubiquitin ligase complex; • GO:0009327 protein-containing complex;
Prosesau biolegol	• protein K48-linked ubiquitination; • BMP signaling pathway; • protein polyubiquitination; • GO:1901227 negative regulation of transcription by RNA polymerase II; • anaphase-promoting complex-dependent catabolic process; • positive regulation of protein ubiquitination; • ubiquitin-dependent protein catabolic process; • protein ubiquitination; • protein deubiquitination; • positive regulation of protein polyubiquitination; • protein targeting to peroxisome; • regulation of mitotic cell cycle phase transition; • MyD88-independent toll-like receptor signaling pathway; • TRIF-dependent toll-like receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologau
	7321
	n/a
	ENSG00000072401
	n/a
	P51668
	n/a
	NM_003338; NM_001204880
	n/a
	NP_001191809; NP_003329
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UBE2D1 yw UBE2D1 a elwir hefyd yn Ubiquitin conjugating enzyme E2 D1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 10, band 10q21.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UBE2D1.

SFT
UBCH5
UBC4/5
UBCH5A
E2(17)KB1

Llyfryddiaeth

"Functional expression cloning and characterization of SFT, a stimulator of Fe transport. ". J Cell Biol. 1997. PMID 9362508.
"Detection and characterization of the in vitro e3 ligase activity of the human MID1 protein. ". J Mol Biol. 2011. PMID 21296087.
"UbcH5A, a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, a stimulator of iron transport, and is up-regulated in hereditary hemochromatosis. ". Blood. 2003. PMID 12480712.
"Assignment of UBE2D1 to human chromosome bands 10q11.2-->q21 by in situ hybridization. ". Cytogenet Cell Genet. 1998. PMID 10072594.
"Characterization and chromosomal mapping of the human gene for SFT, a stimulator of Fe transport.". Biochem Biophys Res Commun. 1998. PMID 9918797.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] UBE2D1 - Cronfa NCBI

[1]

[2]