UGT2B10

UGT2B10
Dynodwyr
Cyfenwau	UGT2B10, UDPGT2B10, UDP glucuronosyltransferase family 2 member B10
Dynodwyr allanol	OMIM: 600070 HomoloGene: 117389 GeneCards: UGT2B10
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• glycosyltransferase activity; • transferase activity; • hexosyltransferase activity; • glucuronosyltransferase activity; • UDP-glycosyltransferase activity;
Cydrannau o'r gell	• integral component of membrane; • organelle membrane; • endoplasmic reticulum membrane; • intracellular membrane-bounded organelle; • Reticwlwm endoplasmig; • bilen;
Prosesau biolegol	• metabolaeth; • lipid metabolism;
	Sources:Amigo / QuickGO
Orthologau
	7365
	n/a
	ENSG00000275190; ENSG00000109181
	n/a
	P36537
	n/a
	NM_001290091; NM_001075; NM_001144767
	n/a
	NP_001066; NP_001138239; NP_001277020
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UGT2B10 yw UGT2B10 a elwir hefyd yn UDP glucuronosyltransferase family 2 member B10 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4q13.2.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UGT2B10.

UDPGT2B10

Llyfryddiaeth

"UGT2B10 genotype influences nicotine glucuronidation, oxidation, and consumption. ". Cancer Epidemiol Biomarkers Prev. 2010. PMID 20501767.
"Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines. ". Pharmacogenet Genomics. 2008. PMID 18300939.
"Human UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme Inhibition. ". Drug Metab Dispos. 2016. PMID 26669329.
"Nicotine N-glucuronidation relative to N-oxidation and C-oxidation and UGT2B10 genotype in five ethnic/racial groups. ". Carcinogenesis. 2014. PMID 25233931.
"Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density.". Breast Cancer Res. 2010. PMID 20799965.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] UGT2B10 - Cronfa NCBI

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[2]