YWHAQ

YWHAQ
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2BTP, 5IQP
Dynodwyr
Cyfenwau	YWHAQ, 14-3-3, 1C5, HS1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Dynodwyr allanol	OMIM: 609009 HomoloGene: 105677 GeneCards: YWHAQ
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• transmembrane transporter binding; • protein domain specific binding; • protein N-terminus binding; • 14-3-3 protein binding; • protein C-terminus binding; • GO:0001948, GO:0016582 protein binding; • identical protein binding;
Cydrannau o'r gell	• cytoplasm; • cytosol; • bilen; • focal adhesion; • extracellular exosome; • cytoplasmic vesicle membrane; • mitocondria; • GO:0009327 protein-containing complex; • synapse;
Prosesau biolegol	• protein targeting; • substantia nigra development; • negative regulation of ion transmembrane transport; • positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; • membrane organization; • GO:0045996 negative regulation of transcription, DNA-templated; • small GTPase mediated signal transduction;
	Sources:Amigo / QuickGO
Orthologau
	10971
	n/a
	ENSG00000134308
	n/a
	P27348
	n/a
	NM_006826
	n/a
	NP_006817
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn YWHAQ yw YWHAQ a elwir hefyd yn Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p25.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn YWHAQ.

1C5
HS1
14-3-3

Llyfryddiaeth

"Role of cortactin homolog HS1 in transendothelial migration of natural killer cells. ". PLoS One. 2015. PMID 25723543.
"A structured proteomic approach identifies 14-3-3Sigma as a novel and reliable protein biomarker in panel based differential diagnostics of liver tumors. ". Biochim Biophys Acta. 2015. PMID 25448011.
"Incremental Expression of 14-3-3 Protein Beta/Alpha in Urine Correlates with Advanced Stage and Poor Survival in Patients with Clear Cell Renal Cell Carcinoma. ". Asian Pac J Cancer Prev. 2016. PMID 27039779.
"Extracellular vesicle-mediated phenotype switching in malignant and non-malignant colon cells. ". BMC Cancer. 2015. PMID 26231887.
"Tanshinone IIA inhibits the proliferation, migration and invasion of ectopic endometrial stromal cells of adenomyosis via 14-3-3ζ downregulation.". Arch Gynecol Obstet. 2015. PMID 26054824.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] YWHAQ - Cronfa NCBI

[1]

[2]