REG4

REG4
ساختارهای موجود
PDB	جستجوی هم‌ساخت‌شناسی: PDBe RCSB
فهرست شناسه‌های PDB
	2KV3
معین‌کننده‌ها
نام‌های دیگر	REG4, GISP, REG-IV, RELP, regenerating family member 4
شناسه‌های بیرونی	OMIM: 609846 MGI: 1914959 HomoloGene: 41671 GeneCards: REG4
موقعیت ژن (موش)
کروموزوم	کروموزوم ۳ (موش)
پایان	98,144,064 bp
هستی‌شناسی ژن
عملکرد ملکولی	• calcium ion binding; • heparin binding; • mannan binding; • carbohydrate binding; • transmembrane signaling receptor activity;
ترکیبات سلولی	• سیتوپلاسم; • extracellular region;
فرایند زیستی	• response to bacterium;
	منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
	83998
	67709
	ENSG00000134193
	ENSMUSG00000027876
	Q9BYZ8
	Q9D8G5
	NM_001159352، NM_001159353 NM_032044، NM_001159352، NM_001159353
	XM_017319697 NM_026328، XM_017319697
	NP_001152825، NP_114433 NP_001152824، NP_001152825، NP_114433
	XP_017175186 NP_080604، XP_017175186
	ویکی‌داده
مشاهده/ویرایش انسان	مشاهده/ویرایش موش

پروتئین ۴ بازسازی‌کنندهٔ مشتق از جزایر لوزالمعده (انگلیسی: Regenerating islet-derived protein 4) یک پروتئین است که در انسان توسط ژن «REG4» کُدگذاری می‌شود.^[۴]^[۵]^[۶]

منابع

↑ ^۱٫۰ ^۱٫۱ ^۱٫۲ GRCm38: Ensembl release 89: ENSMUSG00000027876 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Hartupee JC, Zhang H, Bonaldo MF, Soares MB, Dieckgraefe BK (Apr 2001). "Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV". Biochim Biophys Acta. 1518 (3): 287–93. doi:10.1016/s0167-4781(00)00284-0. PMID 11311942.
↑ Violette S, Festor E, Pandrea-Vasile I, Mitchell V, Adida C, Dussaulx E, Lacorte JM, Chambaz J, Lacasa M, Lesuffleur T (Nov 2002). "Reg IV, a new member of the regenerating gene family, is overexpressed in colorectal carcinomas". Int J Cancer. 103 (2): 185–93. doi:10.1002/ijc.10788. PMID 12455032.
↑ "Entrez Gene: REG4 regenerating islet-derived family, member 4".

مشارکت‌کنندگان ویکی‌پدیا. «REG4». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۲۲ دسامبر ۲۰۱۹.

برای مطالعهٔ بیشتر

Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Kämäräinen M; Heiskala K; Knuutila S; et al. (2003). "RELP, a Novel Human Reg-Like Protein with Up-Regulated Expression in Inflammatory and Metaplastic Gastrointestinal Mucosa". Am. J. Pathol. 163 (1): 11–20. doi:10.1016/S0002-9440(10)63625-5. PMC 1868159. PMID 12819006. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Zhang Y; Lai M; Lv B; et al. (2003). "Overexpression of Reg IV in colorectal adenoma". Cancer Lett. 200 (1): 69–76. doi:10.1016/S0304-3835(03)00460-9. PMID 14550954. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Ota T; Suzuki Y; Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Gu Z; Rubin MA; Yang Y; et al. (2005). "Reg IV: a promising marker of hormone refractory metastatic prostate cancer". Clin. Cancer Res. 11 (6): 2237–43. doi:10.1158/1078-0432.CCR-04-0356. PMID 15788672. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Bishnupuri KS; Luo Q; Murmu N; et al. (2006). "Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas". Gastroenterology. 130 (1): 137–49. doi:10.1053/j.gastro.2005.10.001. PMID 16401477. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Gregory SG; Barlow KF; McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Takehara A; Eguchi H; Ohigashi H; et al. (2006). "Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4". Cancer Sci. 97 (11): 1191–7. doi:10.1111/j.1349-7006.2006.00297.x. PMID 16918991. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)

این یک مقالهٔ خرد زیست‌شناسی مولکولی است. می‌توانید با گسترش آن به ویکی‌پدیا کمک کنید.

[refGRCm38Ensembl-1] ۱٫۰ ^۱٫۱ ^۱٫۲ GRCm38: Ensembl release 89: ENSMUSG00000027876 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11311942-4] Hartupee JC, Zhang H, Bonaldo MF, Soares MB, Dieckgraefe BK (Apr 2001). "Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV". Biochim Biophys Acta. 1518 (3): 287–93. doi:10.1016/s0167-4781(00)00284-0. PMID 11311942.

[pmid12455032-5] Violette S, Festor E, Pandrea-Vasile I, Mitchell V, Adida C, Dussaulx E, Lacorte JM, Chambaz J, Lacasa M, Lesuffleur T (Nov 2002). "Reg IV, a new member of the regenerating gene family, is overexpressed in colorectal carcinomas". Int J Cancer. 103 (2): 185–93. doi:10.1002/ijc.10788. PMID 12455032.

[entrez-6] "Entrez Gene: REG4 regenerating islet-derived family, member 4".

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