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کنترل مهاری که به آن مهار پاسخ نیز میگویند، یک فرایند شناختی است و بهطور خاصتر، یک عملکرد اجرایی - این به فرد اجازه میدهد تا از انگیزههای خود و پاسخهای رفتاری طبیعی، عادی یا مسلط به محرکها (a.k.a. همان پاسخهای پیش توان) جلوگیری کند تا رفتار مناسب تری را که با تحقق اهداف آنها سازگار است ، انتخاب کند.[۱] خود کنترلی جنبه مهمی از کنترل مهاری است.[۲][۳] به عنوان مثال، سرکوب موفقیتآمیز پاسخ رفتاری طبیعی برای خوردن کیک هنگامی که فرد هوس آن را میکند در حالی که رژیم غذایی به سر میبرد نیاز به استفاده از کنترل مهاری دارد.
قشر جلوی پیشانی، هسته دمی و هسته ساب تالاموس برای تنظیم شناخت کنترل مهاری شناخته شدهاند. کنترل بازدارندگی هم در اعتیاد و هم در اختلال بیش فعالی با کمبود توجه مختل میشود.[۴] در بزرگسالان سالم و افراد مبتلا به ADHD ، کنترل مهاری با دوزهای کم (درمانی) متیل فنیدیت یا آمفتامین در کوتاه مدت بهبود مییابد.[۱][۵] کنترل مهاری نیز ممکن است در طولانی مدت از طریق ورزش هوازی مداوم بهبود یابد.[۲][۳]
آزمون کنترل مهاری نوعی آزمایش عصب روانشناختی است که توانایی فرد را برای غلبه بر پاسخ رفتاری طبیعی، عادی یا مسلط به محرک برای پیادهسازی رفتارهای goal-oriented پذیرانه سازگارترکند.[۱] برخی از آزمایشهای عصب روانشناختی که کنترل مهاری را اندازهگیری میکنند شامل Stroop task, go/no-go task, Simon task, Flanker task, antisaccade tasks, delay of gratification tasks, and stop-signal tasksاست.
زنها تمایل دارند که ظرفیت پایه بیشتری برای اعمال کنترل بازدارندگی بر رفتارهای ناخواسته یا عادت داشته باشند و به عوامل متناسب با محیط تعدیل کننده نسبت به مردها واکنش متفاوتی نشان دهند.[۶][۷] به عنوان مثال، گوش دادن به موسیقی بهطور قابل توجهی سرعت مهار پاسخ را در زنان بهبود میبخشد، اما میزان مهار پاسخ را در مردان کاهش میدهد.
Executive functions are strategic in nature and depend on higher-order cognitive processes that underpin planning, sustained attention, selective attention, resistance to interference, volitional inhibition, working memory, and mental flexibility ... Data to date from studies of aging provide strong evidence of exercise-linked benefits related to task switching, selective attention, inhibition of prepotent responses, and working memory capacity; furthermore, cross-sectional fitness data suggest that working memory updating could potentially benefit as well. In young adults, working memory updating is the main executive function shown to benefit from regular exercise, but cross-sectional data further suggest that task-switching and post-error performance may also benefit. In children, working memory capacity has been shown to benefit, and cross-sectional data suggest potential benefits for selective attention and inhibitory control. ... Support for the idea that higher levels of aerobic activity may be associated with superior brain structure has been gained through cross-sectional studies in older adults and children (for a recent review, see Voss, Nagamatsu, et al. , 2011). ... only those in the aerobic exercise group exhibited improved connectivity between the left and right prefrontal cortices, two areas that are crucial to the effective functioning of the fronto-executive network. ... Together, these studies provide evidence that regular aerobic exercise benefits control over responses during selective attention in older adults. ... aerobic fitness is a good predictor of performance on tasks that rely relatively heavily on inhibitory control over prepotent responses (e.g. , Colcombe et al. , 2004, Study 1; Prakash et al. , 2011) and also that regular aerobic exercise improves performance on such tasks ... Overall, the results from the span and Sternberg tasks suggest that regular exercise can also confer benefits for the volume of information that children and older adults can hold in mind at one time.
Recent theory (e.g. , Temporal Self-Regulation Theory; Hall and Fong, 2007, 2010, 2013) and evidence suggest that the relation between physical activity and cognitive control is reciprocal (Daly et al. , 2013). Most research has focused on the beneficial effects of regular physical activity on executive functions-the set of neural processes that define cognitive control. Considerable evidence shows that regular physical activity is associated with enhanced cognitive functions, including attention, processing speed, task switching, inhibition of prepotent responses and declarative memory (for reviews see Colcombe and Kramer, 2003; Smith et al. , 2010; Guiney and Machado, 2013; McAuley et al. , 2013). Recent research demonstrates a dose-response relationship between fitness and spatial memory (Erickson et al. , 2011) ... The effects of physical activity on cognitive control appear to be underpinned by a variety of brain processes including: increased hippocampal volume, increased gray matter density in the prefrontal cortex (PFC), upregulation of neurotrophins and greater microvascular density ... Together, this research suggests that an improvement in control processes, such as attention and inhibition or interference control, is associated with an improvement in self-regulation of physical activity. ... Increasingly, research shows that cognitive control abilities are malleable, and that cognitive training can produce positive cognitive outcomes and improvements in daily function (Willis et al. , 2006; Hertzog et al. , 2008) that can have long-lasting effects (Rebok et al. , 2014). Approaches to cognitive training are numerous and varied; however, the relative superiority of different approaches with regard to training and transfer continue to be debated.
Animal and human imaging studies have revealed ... a key role in the preoccupation/anticipation stage for a widely distributed network involving the orbitofrontal cortex-dorsal striatum, prefrontal cortex, basolateral amygdala, hippocampus, and insula involved in craving and the cingulate gyrus, dorsolateral prefrontal, and inferior frontal cortices in disrupted inhibitory control.
Collectively, this evidence indicates that at low, clinically relevant doses, psychostimulants are devoid of the behavioral and neurochemical actions that define this class of drugs and instead act largely as cognitive enhancers (improving PFC-dependent function). This information has potentially important clinical implications as well as relevance for public health policy regarding the widespread clinical use of psychostimulants and for the development of novel pharmacologic treatments for attention-deficit/hyperactivity disorder and other conditions associated with PFC dysregulation. ... In particular, in both animals and humans, lower doses maximally improve performance in tests of working memory and response inhibition, whereas maximal suppression of overt behavior and facilitation of attentional processes occurs at higher doses.
Inhibition of irrelevant responses is an important aspect of cognitive control of a goal-directed behavior. Females and males show different levels of susceptibility to neuropsychological disorders such as impulsive behavior and addiction, which might be related to differences in inhibitory brain functions. ... Here, we show a significant difference in executive control functions and their modulation by contextual factors between females and males