Octocryleno

Octocryleno
instantia de: type of chemical entity[*]
subclasse de: composito chimic
Commons: Octocrylene

Octocryleno es un composito organic controversate usate in cremas solar (ca) o cosmetic. Es un ester obtenite per condensation de 2-ethylhexyl cyanoacetato con benzophenona (en). Es un liquido viscose, clar e sin color. Su formula chimic es C₂₄H₂₇NO₂.

Le conjugation extendite del acrylato portion del molecula absorbe ultraviolette radios con longitudines de unda de 280 ad 320 nm (UVB e UVA de undas curte),^[1] protegente pelle de un damno directe del ADN. Le ethylhexanol portion, un alcohol grasse, confere al producto un proprietate emolliente.

Securitate

Octocryleno se degrada progessivemente^[2] in benzophenona (en), un composito cancerogene, photomutageno e perturbator endocrin, conducente a un concentration significative de benzophenona in tote cremas testate.

In corallo, octocryleno se accumula in forma de conjugatos de acido grasse e genera un dysfunction mitochondrial.^[3]

Regulation

In 2018, Palau prohibe vendita e uso de 3 filtros UV toxic pro corallo, includente octocryleno.^[4]

In Francia, ANSES recommende le interdiction del octocryleno in cremas solar.^[5]

Referentias

1. Smart Skin Care: Octocrylene
2. per retroaldol condensation (en) secundo "Benzophenone Accumulates over Time from the Degradation of Octocrylene in Commercial Sunscreen Products" (7 March 2021). Chemical Research in Toxicology 34 (4): 1046–1054. doi:10.1021/acs.chemrestox.0c00461. PMID 33682414. 
3. "Metabolomics reveal that octocrylene accumulates in Pocillopora damicornis tissues as fatty acid conjugates and triggers coral cell mitochondrial dysfunction" (2019). Analytical Chemistry 91 (1): 990–995. doi:10.1021/acs.analchem.8b04187. PMID 30516955. 
4. RPPL No. 10-30: The Responsible Tourism Education Act of 2018 – PalauGov.pw.
5. Crèmes solaires : l'Anses demande le retrait de l'octocrylène à cause de ses effets sur l'environnement. France Info (2023-07-07).