Kaminaljuyu adalah sebuah situs peradaban Maya pada zaman pra-Kolumbus. Kota Kaminaljuyu terkubur di bawah Kota Guatemala. Situs ini telah disebut-sebut sebagai salah satu situs arkeologi terbesar di benua Amerika oleh Michael Coe,[1] walaupun peninggalan-peninggalan yang tersisa saat ini (beberapa gundukan) tidak terlihat begitu menarik bila dibandingkan dengan situs-situs Maya lainnya yang sering didatangi wisatawan. Situs ini pertama kali dipetakan secara ilmiah oleh E. M. Shook, dan hasilnya menunjukkan bahwa terdapat 200 landasan dan gundukan piramida, dan paling tidak setengah dari antaranya didirikan sebelum berakhirnya zaman Praklasik (250 M).
Kota ini memiliki sejarah yang panjang. Kota ini didirikan pada zaman Praklasik Akhir dan ditinggalkan pada zaman Pascaklasik.
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