Atagabalin

type of chemical entity
obere ụdị nke	chemical compound
usoro kemịkalụ	C₁₀H₁₉NO₂
canonical SMILES	CC1CC(CC1C)(CC(=O)O)CN
isomeric SMILES	C[C@H]1CC(C[C@@H]1C)(CC(=O)O)CN

Atagabalin (PD-0₂00,390) bụ ọgwụ nke Pfizer mepụtara site na afo nwela onwa ma nwee njikọ na gabapentin, nke na-ejikọta ya na ọwa calcium α2δ (1 na 2).^[1] Ọ nọ na mmepe dị ka ọgwụgwọ maka ehighị ụra nke ọma, mana a kwụsịrị ya mgbe nsonaazụ nnwale na-adịghị mma gasịrị.^[2]^[3]^[4]

Hụkwa

4-Methylpregabalin
Gabapentin enacarbil
PD-217,014

Ntụaka

↑ (January 2010) "Synthesis and in vivo evaluation of bicyclic gababutins". Bioorganic & Medicinal Chemistry Letters 20 (2): 461–4. DOI:10.1016/j.bmcl.2009.11.118. PMID 20005103.
↑ (August 2009) "Effect of renal impairment on the pharmacokinetics of PD 0200390, a novel ligand for the voltage-gated calcium channel alpha-2-delta subunit". British Journal of Clinical Pharmacology 68 (2): 174–80. DOI:10.1111/j.1365-2125.2009.03444.x. PMID 19694735.
↑ (May 2011) "Methodology for rapid measures of glutamate release in rat brain slices using ceramic-based microelectrode arrays: Basic characterization and drug pharmacology". Brain Research 1401: 1–9. DOI:10.1016/j.brainres.2011.05.025. PMID 21664606.
↑ (June 2011) "Modeling Sleep Data for a New Drug in Development using Markov Mixed-Effects Models". Pharmaceutical Research 28 (10): 2610–27. DOI:10.1007/s11095-011-0490-x. PMID 21681607.

[pmid20005103-1] (January 2010) "Synthesis and in vivo evaluation of bicyclic gababutins". Bioorganic & Medicinal Chemistry Letters 20 (2): 461–4. DOI:10.1016/j.bmcl.2009.11.118. PMID 20005103.

[pmid19694735-2] (August 2009) "Effect of renal impairment on the pharmacokinetics of PD 0200390, a novel ligand for the voltage-gated calcium channel alpha-2-delta subunit". British Journal of Clinical Pharmacology 68 (2): 174–80. DOI:10.1111/j.1365-2125.2009.03444.x. PMID 19694735.

[pmid21664606-3] (May 2011) "Methodology for rapid measures of glutamate release in rat brain slices using ceramic-based microelectrode arrays: Basic characterization and drug pharmacology". Brain Research 1401: 1–9. DOI:10.1016/j.brainres.2011.05.025. PMID 21664606.

[pmid21681607-4] (June 2011) "Modeling Sleep Data for a New Drug in Development using Markov Mixed-Effects Models". Pharmaceutical Research 28 (10): 2610–27. DOI:10.1007/s11095-011-0490-x. PMID 21681607.

[1]

[2]

[3]

[4]