CCL22

CCL22 (ang C-C motif chemokine 22) – białko z grupy chemokin CC kodowane u człowieka przez gen CCL22^[1]^[2]^[3].

CCL22 wydzielana jest przez komórki dendrytyczne i makrofagi. Przekazuje efekt na komórki docelowe poprzez interakcję z receptorem chemokinowym CCR4 na powierzchni tych komórek^[4]. Gen kodujący CCL22 leży na chromosomie 16, w klasterze razem z innymi genami kodującymi cytokiny CX3CL1 i CCL17^[5]^[6].

Przypisy

↑ Godiska R, Chantry D, Raport CJ, Sozzani S, Allavena P, Leviten D, Mantovani A, Gray PW. Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells. „J Exp Med”. 185 (9), s. 1595–604, Jun 1997. DOI: 10.1084/jem.185.9.1595. PMID: 9151897. PMCID: PMC2196293.
↑ Nomiyama H, Imai T, Kusuda J, Miura R, Callen DF, Yoshie O. Human chemokines fractalkine (SCYD1), MDC (SCYA22) and TARC (SCYA17) are clustered on chromosome 16q13. „Cytogenet Cell Genet”. 81 (1), s. 10–1, Oct 1998. DOI: 10.1159/000015000. PMID: 9691168.
↑ Entrez Gene: CCL22 chemokine (C-C motif) ligand 22.
↑ Vulcano M, Albanesi C, Stoppacciaro A, Bagnati R, D'Amico G, Struyf S, Transidico P, Bonecchi R, Del Prete A, Allavena P, Ruco LP, Chiabrando C, Girolomoni G, Mantovani A, Sozzani S. Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo. „Eur. J. Immunol.”. 31 (3), s. 812–22, 2001. DOI: <812::AID-IMMU812>3.0.CO;2-L 10.1002/1521-4141(200103)31:3<812::AID-IMMU812>3.0.CO;2-L. PMID: 11241286.
↑ Nomiyama H, Imai T, Kusuda J, Miura R, Callen DF, Yoshie O. Human chemokines fractalkine (SCYD1), MDC (SCYA22) and TARC (SCYA17) are clustered on chromosome 16q13. „Cytogenet. Cell Genet.”. 81 (1), s. 10–1, 1998. DOI: 10.1159/000015000. PMID: 9691168.
↑ Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, Mason T, Crosby ML, Barnstead M, Cronin L, Deslattes Mays A, Cao Y, Xu RX, Kang HL, Mitchell S, Eichler EE, Harris PC, Venter JC, Adams MD. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. „Genomics”. 60 (3), s. 295–308, 1999. DOI: 10.1006/geno.1999.5927. PMID: 10493829.

[pmid9151897-1] Godiska R, Chantry D, Raport CJ, Sozzani S, Allavena P, Leviten D, Mantovani A, Gray PW. Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells. „J Exp Med”. 185 (9), s. 1595–604, Jun 1997. DOI: 10.1084/jem.185.9.1595. PMID: 9151897. PMCID: PMC2196293.

[pmid9691168-2] Nomiyama H, Imai T, Kusuda J, Miura R, Callen DF, Yoshie O. Human chemokines fractalkine (SCYD1), MDC (SCYA22) and TARC (SCYA17) are clustered on chromosome 16q13. „Cytogenet Cell Genet”. 81 (1), s. 10–1, Oct 1998. DOI: 10.1159/000015000. PMID: 9691168.

[entrez-3] Entrez Gene: CCL22 chemokine (C-C motif) ligand 22.

[pmid11241286-4] Vulcano M, Albanesi C, Stoppacciaro A, Bagnati R, D'Amico G, Struyf S, Transidico P, Bonecchi R, Del Prete A, Allavena P, Ruco LP, Chiabrando C, Girolomoni G, Mantovani A, Sozzani S. Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo. „Eur. J. Immunol.”. 31 (3), s. 812–22, 2001. DOI: <812::AID-IMMU812>3.0.CO;2-L 10.1002/1521-4141(200103)31:3<812::AID-IMMU812>3.0.CO;2-L. PMID: 11241286.

[autogenerated1-5] Nomiyama H, Imai T, Kusuda J, Miura R, Callen DF, Yoshie O. Human chemokines fractalkine (SCYD1), MDC (SCYA22) and TARC (SCYA17) are clustered on chromosome 16q13. „Cytogenet. Cell Genet.”. 81 (1), s. 10–1, 1998. DOI: 10.1159/000015000. PMID: 9691168.

[pmid10493829-6] Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, Mason T, Crosby ML, Barnstead M, Cronin L, Deslattes Mays A, Cao Y, Xu RX, Kang HL, Mitchell S, Eichler EE, Harris PC, Venter JC, Adams MD. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. „Genomics”. 60 (3), s. 295–308, 1999. DOI: 10.1006/geno.1999.5927. PMID: 10493829.

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