Receptor metabotrópico de glutamato 7

Glutamate metabotropic receptor 7
Identificadores
Nomes alternativos
IDs externosGeneCards: [1]
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O receptor metabotrópico de glutamato 7 é uma proteína que em seres humanos é codificada pelo gene GRM7.[1][2][3][4] Os receptores metabotrópicos de glutamato são uma família de receptores acoplados à proteína G.

Interações

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O receptor metabotrópico de glutamato 7 mostrou interação com a proteína quinase C 1 (PICK1 [en]).[5]

Referências

  1. ↑ Chad J. Swanson, Mark Bures, Michael P. Johnson, Anni-Maija Linden, James A. Monn & Darryle D. Schoepp. «Metabotropic glutamate receptors as novel targets for anxiety and stress disorders» (em inglês). fevereiro de 2005. Consultado em 1 de julho de 2010 
  2. ↑ Okamoto N, Hori S, Akazawa C, Hayashi Y, Shigemoto R, Mizuno N, Nakanishi S (1994). «Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction». J Biol Chem. 269 (2): 1231–6. PMID 8288585 
  3. ↑ Makoff A, Pilling C, Harrington K, Emson P (1997). «Human metabotropic glutamate receptor type 7: molecular cloning and mRNA distribution in the CNS». Brain Res Mol Brain Res. 40 (1): 165–70. PMID 8840028. doi:10.1016/0169-328X(96)00110-6 
  4. ↑ «Entrez Gene: GRM7 glutamate receptor, metabotropic 7» 
  5. ↑ Dev, K K; Nakajima Y, Kitano J, Braithwaite S P, Henley J M, Nakanishi S (2000). «PICK1 interacts with and regulates PKC phosphorylation of mGLUR7». UNITED STATES. J. Neurosci. 20 (19): 7252–7. PMID 11007882 

Bibliografia

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  • Scherer SW, Duvoisin RM, Kuhn R; et al. (1997). «Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q.». Genomics. 31 (2): 230–3. PMID 8824806. doi:10.1006/geno.1996.0036 
  • Flor PJ, Van Der Putten H, Rüegg D; et al. (1997). «A novel splice variant of a metabotropic glutamate receptor, human mGluR7b.». Neuropharmacology. 36 (2): 153–9. PMID 9144652. doi:10.1016/S0028-3908(96)00176-1 
  • Wu S, Wright RA, Rockey PK; et al. (1998). «Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells.». Brain Res. Mol. Brain Res. 53 (1-2): 88–97. PMID 9473604. doi:10.1016/S0169-328X(97)00277-5 
  • Nakajima Y, Yamamoto T, Nakayama T, Nakanishi S (1999). «A relationship between protein kinase C phosphorylation and calmodulin binding to the metabotropic glutamate receptor subtype 7.». J. Biol. Chem. 274 (39): 27573–7. PMID 10488094. doi:10.1074/jbc.274.39.27573 
  • O'Connor V, El Far O, Bofill-Cardona E; et al. (1999). «Calmodulin dependence of presynaptic metabotropic glutamate receptor signaling.». Science. 286 (5442): 1180–4. PMID 10550060. doi:10.1126/science.286.5442.1180 
  • Barbon A, Ferraboli S, Barlati S (2000). «Assignment of the human metabotropic glutamate receptor gene GRM7 to chromosome 3p26.1→p25.2 by radiation hybrid mapping.». Cytogenet. Cell Genet. 88 (3-4). 288 páginas. PMID 10828612. doi:10.1159/000015541 
  • Dev KK, Nakajima Y, Kitano J; et al. (2001). «PICK1 interacts with and regulates PKC phosphorylation of mGLUR7.». J. Neurosci. 20 (19): 7252–7. PMID 11007882 
  • Bolonna AA, Kerwin RW, Munro J; et al. (2001). «Polymorphisms in the genes for mGluR types 7 and 8: association studies with schizophrenia.». Schizophr. Res. 47 (1): 99–103. PMID 11163549. doi:10.1016/S0920-9964(99)00235-2 
  • Hirbec H, Perestenko O, Nishimune A; et al. (2002). «The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs.». J. Biol. Chem. 277 (18): 15221–4. PMID 11891216. doi:10.1074/jbc.C200112200 
  • Enz R (2002). «The actin-binding protein Filamin-A interacts with the metabotropic glutamate receptor type 7.». FEBS Lett. 514 (2-3): 184–8. PMID 11943148. doi:10.1016/S0014-5793(02)02361-X 
  • Saugstad JA, Yang S, Pohl J; et al. (2002). «Interaction between metabotropic glutamate receptor 7 and alpha tubulin.». J. Neurochem. 80 (6): 980–8. PMID 11953448. doi:10.1046/j.0022-3042.2002.00778.x 
  • Schulz HL, Stohr H, Weber BH (2002). «Characterization of three novel isoforms of the metabotrobic glutamate receptor 7 (GRM7).». Neurosci. Lett. 326 (1): 37–40. PMID 12052533. doi:10.1016/S0304-3940(02)00306-3 
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). «Complete sequencing and characterization of 21,243 full-length human cDNAs.». Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285 
  • Kobayashi Y, Akiyoshi J, Kanehisa M; et al. (2007). «Lack of polymorphism in genes encoding mGluR 7, mGluR 8, GABA(A) receptor alfa-6 subunit and nociceptin/orphanin FQ receptor and panic disorder.». Psychiatr. Genet. 17 (1). 9 páginas. PMID 17167337. doi:10.1097/YPG.0b013e32801118bc 

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