4-PPBP

4-PPBP
	4-phenyl-1-(4-phenylbutyl) piperidine
Identifikacija
CAS registarski broj	136534-70-8
PubChem	3035672
ChemSpider	2299855
MeSH	4-phenyl-1-(4-phenylbutyl)piperidine
ChEMBL	CHEMBL325238
Jmol-3D slike	Slika 1; Slika 2
SMILES
	C1CN(CCC1C2=CC=CC=C2) CCCCC3=CC=CC=C3 c1ccccc1C3CCN(CCCCc2ccccc2)CC3
InChI
	InChI=1S/C21H27N/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20/h1-6,9-10,12-13,21H,7-8,11,14-18H2 ; Kod: HQGDPZPNAXRCSA-UHFFFAOYSA-N InChI=1/C21H27N/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20/h1-6,9-10,12-13,21H,7-8,11,14-18H2; Kod: HQGDPZPNAXRCSA-UHFFFAOYAV
Svojstva
Molekulska formula	C21H27N
Molarna masa	293.446 g/mol
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

4-PPBP je molekul koji se vezuje za sigma receptore.^[5] Eksperimentalni rezultati ukazuju da PPBP redukuje ćelijsku smrt in vitro putem mehanizma koji je zavistan od zaštitnih gena kao što je bcl-2.

Literatura

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Yang S, Bhardwaj A, Cheng J, Alkayed NJ, Hurn PD, Kirsch JR (May 2007). „Sigma receptor agonists provide neuroprotection in vitro by preserving bcl-2”. Anesthesia and Analgesia 104 (5): 1179–84, tables of contents. DOI:10.1213/01.ane.00002. PMC 2596726. PMID 17456670. Pristupljeno 2011-04-25.

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[pmid17456670-5] Yang S, Bhardwaj A, Cheng J, Alkayed NJ, Hurn PD, Kirsch JR (May 2007). „Sigma receptor agonists provide neuroprotection in vitro by preserving bcl-2”. Anesthesia and Analgesia 104 (5): 1179–84, tables of contents. DOI:10.1213/01.ane.00002. PMC 2596726. PMID 17456670. Pristupljeno 2011-04-25.

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