Diacilglicerol kinaza

Diacilglicerol kinaza
Identifikatori
EC broj	2.7.1.107
CAS broj	60382-71-0
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Diacilglicerol kinaza (EC 2.7.1.107, digliceridna kinaza, 1,2-diacilglicerolna kinaza (fosforilacija), 1,2-diacilglicerolna kinaza, sn-1,2-diacilglicerolna kinaza, DG kinaza, DGK, ATP:diacilglicerol fosfotransferaza, arahidonoil-specifična diacilglicerolna kinaza, diacilglicerol:ATP kinaza, ATP:1,2-diacilglicerol 3-fosfotransferaza) je enzim sa sistematskim imenom ATP:1,2-diacil-sn-glicerol 3-fosfotransferaza.^[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + 1,2-diacil-sn-glicerol ${\displaystyle \rightleftharpoons }$ ADP + 1,2-diacil-sn-glicerol 3-fosfat

Reference

1. Daleo, G.R., Piras, M.M. and Piras, R. (1976). „Diglyceride kinase activity of microtubules. Characterization and comparison with the protein kinase and ATPase activities associated with vinblastine-isolated tubulin of chick embryonic muscles”. Eur. J. Biochem. 68: 339-346. PMID 185051. 
2. Hokin, L.E. and Hokin, M.R. (1963). „Diglyceride kinase and other pathways for phosphatidic acid synthesis in the erythrocyte membrane”. Biochim. Biophys. Acta 67: 470-484. PMID 13961253. 
3. Weissbach, H., Thomas, E. and Kaback, H.R. (1971). „Studies on the metabolism of ATP by isolated bacterial membranes: formation and metabolism of membrane-bound phosphatidic acid”. Arch. Biochem. Biophys. 147: 249-254. PMID 4940043. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Spoljašnje veze

• MeSH Diacylglycerol+kinase+(ATP+dependent)