Endopeptidaza K
| Endopeptidaza K | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.21.64 | ||||||||
| CAS broj | 39450-01-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Endopeptidaza K (EC 3.4.21.64, Tritirachium alkaline proteinaza, Tritirachium album serin proteinaza, proteinaza K, Tritirachium album proteinaza K) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza keratina, i drugih proteina sa subtilisinu sličnom specifičnošću. Dolazi do hidrolize peptidnih amida
Ovaj enzim je izolovan iz plesni Tritirachium album Limber.
- ↑ Ebeling, W., Hennrich, N., Klockow, M., Metz, H., Orth, H.D. and Lang, H. (1974). „Proteinase K from Tritirachium album Limber”. Eur. J. Biochem. 47: 91-97. PMID 4373242.
- ↑ Morihara, K. and Tsuzuki, H. (1975). „Specificity of proteinase K from Tritirachium album Limber for synthetic peptides”. Agric. Biol. Chem. 39: 1489-1492.
- ↑ Kraus, E., Klitz, H.H. and Fembert, U.F. (1976). „The specificity of proteinase K against oxidized insulin B chain”. Hoppe-Seyler's Z. Physiol. Chem. 357: 233-237. PMID 943367.
- ↑ Jany, K.-D., Lederer, G. and Mayer, B. (1986). „Amino acid sequence of proteinase K from the mold Tritirachium album Limber”. FEBS Lett. 199: 139-144.
- ↑ Betzel, C., Teplyakov, A.V., Harutyunyan, E.H., Saenger, W. and Wilson, K.S. (1990). „Thermitase and proteinase K: a comparison of the refined three-dimensional structures of the native enzymes”. Protein Engineering 3: 161-172. PMID 2184432.
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