GMP reduktaza
| GMP reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Identifikatori | |||||||||
| EC broj | 1.7.1.7 | ||||||||
| CAS broj | 9029-32-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
GMP reduktaza (EC 1.7.1.7, guanozin 5'-monofosfatna reduktaza, NADPH:GMP oksidoreduktaza (deaminacija), guanozin monofosfatna reduktaza, guanilatna reduktaza, NADPH2:guanozin-5'-fosfat oksidoreduktaza (deaminacija), guanozin 5'-fosfatna reduktaza) je enzim sa sistematskim imenom inozin-5'-fosfat:NADP+ oksidoreduktaza (aminacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- IMP + NH3 + NADP+ GMP + NADPH + H+
- ↑ MacKenzie, J.J. and Sorensen, L.B. (1973). „Guanosine 5′-phosphate reductase of human erythrocytes”. Biochim. Biophys. Acta 327: 282-294. PMID 4149840.
- ↑ Mager, J. and Magasanik, B. (1960). „Guanosine 5′-phosphate reductase and its role in the interconversion of purine nucleotides”. J. Biol. Chem. 235: 1474-1478. PMID 14419794.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.